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Brain Tumors. Neurons or Glial cells?. Neurons. Rarely, if ever responsible for tumors Don’t reproduce. Gliomas arise from glial cells. Different types of gliomas: Astrocytic tumors include astrocytomas (less malignant), anaplastic astrocytomas, and glioblastomas (most malignant)
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Brain Tumors Neurons or Glial cells?
Neurons • Rarely, if ever responsible for tumors • Don’t reproduce
Gliomas arise from glial cells • Different types of gliomas: • Astrocytic tumors include astrocytomas (less malignant), anaplastic astrocytomas, and glioblastomas (most malignant) • Oligodendroglial tumors vary in malignancy • Glioblastomas are the most aggressive type of primary brain tumor
Meningiomas • Arise from arachnoidal cells • One of three meniges that compose membrane that covers brain and spinal cord. However, these tumors are mostly (90%) benign
Level of severity • Tumors are graded on multiple factors: • Growth rate • Blood supply • Malignancy • Border distinctness *The ultimate determining factor in classifying tumors is the cell of highest malignancy, even if the overall composition of the tumor is of lesser malignancy.
Diagnosis • Balance, vision, hearing, and reflex tests are conducted to help diagnose brain tumors • MRI’s used with contrast dye are subsequently performed to find tumors and detect their locations.
Treatment • Open cranial surgery • Radiosurgery • Many beams of targeted radiation focus on the tumor from all different directions (one session limit). • Radiotherapy (multi-session) • Chemotherapy
What causes a tumor? • We don’t know yet… • But: • 5% arise from genetic inheritance (usually extra copies chromosome 7) • Environment also plays a role
Bibliography • http://www.willamette.edu/~gorr/classes/cs449/figs/neurons.jpg • http://www.mayoclinic.org/metastatic-brain-tumors/ • http://www.irsa.org/metastatic_tumors.html • http://www.irsa.org/astrocytoma.html • http://www.nlm.nih.gov/medlineplus/ency/article/007222.htm • http://psychology.about.com/od/biopsychology/f/neuron01.htm • http://encefalus.com/wp-content/uploads/2008/09/neuron_2.jpg • http://sakshat.amrita.ac.in/VirtualLab/images/neuron.png • http://tuberose.com/Graphics/brain%20tumor.jpeg • http://www.wired.com/images_blogs/wiredscience/2009/04/neurons1.jpg