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EPIDEMIOLOGY. Ijeoma Nkeiruka Otigbuo. PATHOLOGY, INFECTION, AND DISEASE. . Key Terms. Pathology. Etiology. Pathogenesis. Infection. Disease. Normal Microbiota. Transient Microbiota. Normal Microbiota And Host:Relationship. Symbiosis. Commensalism. Mutualism. Parasitism.
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EPIDEMIOLOGY. Ijeoma Nkeiruka Otigbuo.
PATHOLOGY, INFECTION, AND DISEASE. • Key Terms. • Pathology. • Etiology. • Pathogenesis. • Infection. • Disease.
Normal Microbiota. • Transient Microbiota.
Normal Microbiota And Host:Relationship. • Symbiosis. • Commensalism. • Mutualism. • Parasitism. • Opportunistic Organisms. • Cooperation Among Microorganisms.
ETIOLOGY OF INFECTIOUS DISEASES. • Koch’s Postulates. • Exceptions to Koch’s Postulates: T. pallidum, M. leprae, M. tuberculosis, S. pyogenes.
CLASSIFYING INFECTIOUS DISEASES. • Symptoms. • Signs. • Syndrome. • Communicable Disease. • Contagious Diseases. • Noncommunicable Disease.
OCCURRENCE OF DISEASE. • Incidence. • Prevalence. • Sporadic Disease. • Endemic Disease. • Epidemic Disease. • Pandemic Disease.
Emerging Infectious Diseases. • Severity or Duration of Disease. • Extent of Host Involvement: Local infection, systemic/Generalized infection, Focal infection, Bacteremia, Septicemia, Toxemia, Viremia, Primary infection, Secondary infection, Inapparent/Subclinical infection.
SPREAD OF INFECTION. • Reservoirs of Infection. • Human Reservoirs. • Animal Reservoirs. • Nonliving Reservoirs.
TRANSMISSION OF DISEASE. • Three Principal Routes: • Contact. • Vehicles. • Vectors.
CONTACT TRANSMISSION. • Direct contact: • Person-to-Person. • Indirect Contact: • Fomite. • Droplet.
VEHICLE TRANSMISSION. • Waterborne. • Foodborne. • Airborne.
VECTORS. • Mechanical. • Biological.
PORTALS OF EXIT. • Respiratory Tract. • Gastrointestinal Tract. • Urogenita Tract • Skin/Wound Infections.
NOSOCOMIAL INFECTIONS. • Microorganisms in the Hospital. • The Compromised Host. • Chain of Transmission.Control of Nosocomial Infections.
PATTERNS OF DISEASE. • Predisposing Factors: • Gender. • Genetic Background. • Climate. • Inadequate Nutrition. • Fatigue. • Age.
Environment. • Habits. • Life-style or Occupation. • Preexisting Illness. • Chemotherapy. • Emotional Disturbances.
DEVELOPMENT OF DISEASE. • Period of Incubation. • Prodromal Period. • Period of Illness. • Period of Decline. • Period of Convalescence.