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How to write a basic research article to be relevant for the readers of European Urology. Jean-Nicolas CORNU Associate Editor European Urology. Context. Basic research Leads to new knowledge Provides scientific capital
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How to write a basic research article to be relevant for the readers of European Urology Jean-Nicolas CORNU Associate Editor European Urology
Context • Basic research • Leads to new knowledge • Providesscientific capital • Is the fundfromwhich the practical applications of knowledge must bedrawn National Science Foundation, 1953
Cancer Functional Kidney/stones Andrology/male Urogynecology Courtesy of the National Cancer Institute (NCI/NIH)
EuropeanUrologycontext High-impact Broad readership Mostlyfocused on clinical issues / patients care « Relative relevance » Clinical implications / applications Translationalwork Please tell us the whole story…
Reasons for rejection We DO WANT YOUR BEST WORK IN EUR UROL Please, understand the concept of primary rejection… • Tooweak (major issue for basic science) • Toofocused (one slice of salami) • Not relevant for all readers (model) • Resultsconsisting in purelytechnical aspects
How to optimize • TOPIC: isiturology or about urology • RESEARCH QUESTION: relevant for a urologist ? • RATIONALE: makeitobvious for a urologist – itrequires a clinicalcontext • METHODS: describeeverything – DO USE supplementary data / supplementarymethods • RESULTS: makeyourwork « talk » to a urologistoptimizeyour displays (spendenough t/e/m) – DO USE supplementary data / supplementarymethods • INTERPRETATION: beaccurate – and relevant
Good examples • Self explanatorytitle • Couldbe of interest for urologists
Rationale/objectives General context … Quick summary of knownpriciples … Rationale for studyingmechanisms … Clearstatement Quicklysaywhydoesitmakesense
Methods Enoughdetailed and referenced to bereproduced Use of appendix
Methods • Keep itsimple, organizedandstraightforward • Descriptionsshouldbecrispandaccurate (wordcount!) – usesuppldata • Statisticsneedtobeclearlydefined (it‘syourtool – aswellassubjects – will bereviewed !!) • Ethicalpermissionhastobegiven – referenceshavetobeadequate • Ifthemethodssectionisunclear, thems will fail!
Up to… whatyouwant • Supplementary content islike « alwaysnecessary » in a big basic research • Alwaysbetterthanpublishing • the ideas • thenmethods • Results in salami • Applications/extensions you have already in the box Tell a story !!
Presentingresultsrules Short but answeringthequestions Refertopicturesandtables - The textisyourspeech - Science is in thetablesandfigures Use sub-sectionshelptoenhancereadibility Beaccurate, credible(units!) Do not overinterpretatthisstage
Discussion • Not too long • Put youresults in perspective • Explian the potential relevance • Generate (reasonable) new hypothesis • Do not make pure statements • Do not sell the paperatthis time: Lessis more, data are everything
Conclusion • Study needstobe relevant forclinicians ++++ • Original / Novel • Ifthestudyis not ofinterestfor a broadreadership in EurUrol, itmaybemoreadequateforsubmissionto a specializedjournal (e.g. ifyoudescribe a newmethodor a specifictechnique): youwon‘t lose time • Critical importanceofmaterial & methods • Figuresandtablesarethmostimportantpartoftheworkandneedyourenergy • Discussion: put in perspective • Sufficientamountofdata / convincingtechniquestosupporttheconclusion : do not overinterpret