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Renal Manifestations of Tuberous Sclerosis Complex

Renal Manifestations of Tuberous Sclerosis Complex. Program Goal. What Is TSC?. “Végétations Vasculaires” (1835). “Sclérose Tubéreuse des Circonvolutions Cérébrales ” (1880). Manifestations of TSC. TSC Clinical Diagnostic Criteria NIH Consensus Conference, Annapolis, Maryland, 1998.

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Renal Manifestations of Tuberous Sclerosis Complex

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  1. Renal Manifestations of Tuberous Sclerosis Complex

  2. Program Goal

  3. What Is TSC?

  4. “Végétations Vasculaires” (1835)

  5. “Sclérose Tubéreuse des Circonvolutions Cérébrales” (1880)

  6. Manifestations of TSC

  7. TSC Clinical Diagnostic CriteriaNIH Consensus Conference, Annapolis, Maryland, 1998

  8. TSC Clinical Diagnostic Criteria (cont)

  9. Genetics of TSC

  10. Pathobiology of TSC

  11. Clinical Manifestations of TSC

  12. Onset of TSC Symptoms With Age

  13. Angiomyolipomas and Development

  14. Cell-of-Origin Hypothesis

  15. PEComas: Angiomyolipomas

  16. TSC Proteins and Cell Growth

  17. TSC Renal Cystic Disease

  18. Other Solid Renal Lesions

  19. Common Presentation of TSC

  20. Diagnosis of TSC

  21. Angiomyolipomas: Ultrasound Images

  22. Angiomyolipomas: CT Scan

  23. Angiomyolipomas: MRI

  24. Role of Biopsy

  25. TSC Prognosis

  26. TSC Prognosis (cont)

  27. Management of TSC

  28. Angiomyolipoma Treatment: Sirolimus

  29. Changes in Volume of Angiomyolipomasa

  30. Everolimus

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