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Tests of Significance

Tests of Significance. t-test (3) – comparison of means F-test – comparison of std. dev. Grubbs test – detect outliers. t-Tests. Case 1 Case 2 Case 3. OR. Sample vs. Analyte. We analyze a sample We determine analytes Analytes – Components of a sample. Correct statements:

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Tests of Significance

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  1. Tests of Significance • t-test (3) – comparison of means • F-test – comparison of std. dev. • Grubbs test – detect outliers

  2. t-Tests • Case 1 • Case 2 • Case 3 OR

  3. Sample vs. Analyte • We analyze a sample • We determine analytes Analytes – Components of a sample

  4. Correct statements: -A Patient’s blood was analyzed for Na, K, and lactose. -The Na, K, and lactose concentrations in a patient’s blood were determined.

  5. Standardization and Calibration Titration: Use of standardized solution to determine the concentration of an unknown. Relies on: • Reaction of known stoichiometry • Solution with a reactant with well-known concentration • ID of an eq. pt.

  6. Properties of Primary Standard • High purity • Stable in atm (not hygroscopic) • Stable to drying • Modest cost • Reasonable solubility • Relatively large MM • React fast • React completely

  7. Standardization and Calibration Titration: Use of standardized solution to determine the concentration of an unknown. External standard calibration: Often, signal response is determined from a series of standards of known concentration to determine the signal response vs. concentration relationship. The concentration of an unknown can be determined directly from this calibration curve.

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