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HIV-1 p6 (31- 46) constructs Binding to Alix

A. HIV-1 p6 (31- 46) constructs Binding to Alix 31 I D K E L Y P L T S L R S L F G 46 A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - -

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HIV-1 p6 (31- 46) constructs Binding to Alix

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  1. A HIV-1 p6 (31- 46) constructs Binding to Alix 31I D K E L Y P L T S L R S L F G46 A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A - - - - - - - - - - - - - - - - A Binding motif . . . E L Y P L . . L R . L . . Relative b-Gal activity 0 0.75 0.25 0.50 1.00 Relative b-Gal activity B 0.75 0 0.25 0.50 1.00 1.25 1.50 p6 ALIX DPRR D716-768 D541-582 D541-582 V509A D541-582 F676D p9 p6 p9 p6 p9 p6 p9 p6 p9

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