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BREAST CANCER OVERVIEW Polly Stephens, M.D. BREAST ANATOMY. breastcancer.org . Ductal Carcinoma In Situ. Calcifications. CALCIFICATIONS. The . Invasive Ductal Carcinoma. Breast cancer. Breast cancer. Vascular/Lymphatic Invasion. Bone scan. Liver metastases. MAMMOGRAPHY.
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MAMMOGRAPHY In America, most breast cancers are diagnosed on mammogram • 1st mammogram age 35 • Or 10 years before your mother was diagnosed with breast cancer • Yearly starting age 40 • About 10% of cancers are not seen on mammogram. DO YOUR OWN EXAM
BIOPSY • Ultrasound-guided • Stereotactic • MRI guided biopsy
INVASIVE DUCTAL CARCINOMA • Overall survival 75% • Stage • 0 Ductal carcinoma in situ • I tumor <2cm, no lymph nodes • II tumor 2-5cm, <4 lymph nodes • III tumor >5cm, >4 lymph nodes • IV distant metastases
INFLAMMATORY BREAST CANCER • P’eau d’orange
Treatment • Local control • Lumpectomy/mastectomy • Radiation • Distal control • Chemotherapy
Who needs chemotherapy? • If there is a risk of cells in the blood stream looking for a place to settle • Bone, Liver, Lung, Brain • There is no blood test for breast cancer cells in the blood stream
Genetics • BRCA 1 and 2 • Alterations or mutations in these genes increase ones risk for breast and ovarian cancer • Only about 5% of breast cancer patients are BRCA +