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Breast Cancer . By: Vincent Russo And Scott Jeffery . Introduction. Impact What is Breast Cancer? Breast Cancer Symbol . Effected Areas. Ductal Cancer Carry Milk Lobule Cancer Make Milk. Genes Involved. BRCA-1 Breast cancer early onset BRCA2 Tumor suppressors
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Breast Cancer By: Vincent Russo And Scott Jeffery
Introduction Impact What is Breast Cancer? Breast Cancer Symbol
Effected Areas Ductal Cancer Carry Milk Lobule Cancer Make Milk
Genes Involved • BRCA-1 • Breast cancer early onset • BRCA2 • Tumor suppressors • Tumor Suppressor- help prevent cells from grow and dividing too rapidly or in an uncontrolled way. • CDH1 • Instructions Epithelial Cadherin • E-Cadherin- binds cells to make tissue • PTEN • Instructions Proteins
Genes ( Continued) • STK11 • Instructions Serine/threoninekinase 11 • Serine/threoninekinase 11- prevents tumors • TP53 • Instructions P53 Tumor Suppressor
Symptoms Lumps Swelling Rash Itchy/Dry Red or Blotchy
Diagnosis • Mammogram • Breast MRI • Biopsy
Stages Stage 0- cancer has not spread (non-invasive) Stage I- cancer spreads to different areas (invasive) Up to 2 centimeters No lymph nodes involved Stage II- invasive IIA- cancer cells are in axillary lymph nodes, not in breast OR tumor is up to 2cm, spread to axillary lymph nodes OR larger than 2cm less than 5cm to axillary lymph nodes IIB- tumor larger than 2cm less than 5cm and has not spread to axillarylympth nodes OR larger than 5cm and has not spread to axillary lymph nodes
Stages (Continued) • Stage III- Invasive • IIIA- spread to lymph nodes near breast bone, OR 5cm or less and spread to other structures, Or larger than 5cm and spread to other structures. • IIIB- any size and spread to chest wall and/or skin, OR may spread to axillarylympth nodes clumped to other structures, may spread to lympth nodes near breastbone • IIIC- may have no sign of cancer in breast, if so may spread to chest wall or skin OR spread to lympth nodes above or below collorbone AND may spread to axillarylympth nodes or lympth nodes near breastbone • Stage IV- spread to other organs (invasive)
Complications Blockage Spreading
Prevalence/Epidemiology Age Gender Ethnic Group Statistics
Prevention Check Breasts Annual Examines Mammograms Drugs/ Smoking/ Alcohol Exercise
Treatment Chemotherapy Radiation Therapy
Awareness Walks Commercials Sponsors Days
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Work Cited "Breast Cancer Side Effects." Cancer Compass. Rising Tide, Kft., n.d. Web. 15 Feb. 2010. <http://www.cancercompass.com/breast-cancer-information/ side-effects.htm>. Henderson, Roger, Dr. "Breast Cancer." Net Doctor. Netdoctor.co.uk, 6 May 2009. Web. 15 Feb. 2010. <http://www.netdoctor.co.uk/diseases/facts/ breastcancer.htm>. "Stages of Breast Cancer." Breast Cancer.org. Breastcancer.org, 21 Jan. 2010. Web. 15 Feb. 2010. <http://www.breastcancer.org/symptoms/diagnosis/ staging.jsp>. "Symptoms and Diagnosis." Breast Cancer.org. Breastcancer.org, 27 June 2009. Web. 15 Feb. 2010. <http://www.breastcancer.org/symptoms/>.