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West Nile Virus: in SK Horses 2003 Tasha Epp, DVM MSc graduate student, Epidemiology WCVM

West Nile Virus: in SK Horses 2003 Tasha Epp, DVM MSc graduate student, Epidemiology WCVM. WNV Clinical Cases. Passive system of case identification ‘Clinical case‘ = neurologic symptoms and positive IgM ELISA Telephone interview of owner. Case Information. 64% were < 10 yrs

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West Nile Virus: in SK Horses 2003 Tasha Epp, DVM MSc graduate student, Epidemiology WCVM

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  1. West Nile Virus: in SK Horses 2003Tasha Epp, DVM MSc graduate student, Epidemiology WCVM

  2. WNV Clinical Cases • Passive system of case identification • ‘Clinical case‘ = neurologic symptoms and positive IgM ELISA • Telephone interview of owner

  3. Case Information • 64% were < 10 yrs • 82% were ‘light’ horses • 55% were males • 72% were dark colored • 83% were pleasure horses • 68% had no shelter • 7% were vaccinated • 96% had no travel history

  4. Clinical Picture in SK

  5. Multi-level model • 2-level hierarchy: Horse (130) within RHA (10) • Outcome of interest: • Health status • Significant variables: • Color • Gender • Week of Onset

  6. Interpretation of IgG results • Impact of vaccination on ELISA results • Kinetics of positive IgG result once infected • Identify a cut-point for the ELISA test

  7. Vaccination study Vaccination dates: Nov 20 and Dec 10 Cut-point = 0.300

  8. Kinetics study

  9. WNV Sero-Prevalence • 20 herds • Sampled 10 horses • August and October • IgG and IgM ELISA

  10. IgG results • created 5 regions with 4 herds in each • Originally results reported as Pos or Neg/Susp • 79% were vacc

  11. Thanks • WCVM Equine Health Research Fund • WCVM Interprovincial Graduate Student Fellowship Fund • Saskatchewan Health • Saskatoon Health Region • Saskatchewan Agriculture • Canadian Co-operative Wildlife Health Center • Wyeth Animal Health

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