CU Anschutz Medical Campus Enterprise Launches Revolutionary

1. CU Anschutz Medical Campus Enterprise Launches Revolutionary Drug Test That Takes the Guesswork Out of Drug Use and Misuse New Urine Drug Testing Technology Will Fundamentally Change the Way Pain Management and Addiction Treatment Industries Manage Patients Denver, CO, January 7, 2014 — For the first time, treatment providers will be able to see a completepicture of their patients’ drug use and misuse using a revolutionary new drug test developed byCU Toxicology, a newly launched enterprise of the University of Colorado School of Medicine’sDepartment of Anesthesiology. This non-profit laboratory on the CU Anschutz Medical Campus inAurora, Colo., has developed a groundbreaking and highly sensitive urine drug testing technologythat confidently reveals greater than five times more drug use than any urine drug screen on themarket. “Polypharmacy, or the use of multiple drugs at once, is the newest American epidemic; more thanone in five U.S. citizens are using three or more prescription drugs, and more than one in 10 areusing five or more,” said Jeffrey Galinkin, MD, chief medical officer of CU Toxicology and professorof anesthesiology and pediatrics at the University of Colorado School of Medicine. “Combine thatwith the fact that drug overdose death rates in the U.S. have more than tripled since 1990, andit’s clear the industry is in crisis and desperately needs a more comprehensive urine drug test, likeCU Toxicology’s, to get a true picture of the issues.” Industry standard drug screens typically identify between six and 19 drug classes and requiretreatment professionals to request a second step to confirm results. This cost-prohibitive andtime-intensive process also relies on treatment professionals to pick and choose the drugs theywant screened, which leads to unsuspected drugs being missed. CU Toxicology’s complete drug discovery technology identifies and confirms more than 500 prescription, illicit and over-the-counter drugs in one test, giving treatment professionals a morecomplete picture of their patients’ polypharmacy or multiple drug use. In addition, the highlysensitive test catches drug use that slips under the radar in industry standard drug screens. For example, the test’s lower sensitivity allows CU Toxicology to identify drug use that is below thestandard screen cutoff. In one study, the test reported twice as many positive reports for cocaine,and three times as many positive reports for codeine as a standard screen. In total, CUToxicology’s complete drug discovery technology reports five times more positive results due toincreased sensitivity and a larger catalog of tested drugs. “Until this point, treatment professionals have treated the trunk without knowing that they’re looking at an elephant,” said Dr. Galinkin. “Industry standard drug screens only catch a fraction ofthe drugs that are used by pain management and addiction treatment patients, which can lead toineffective treatment and adverse drug events, such as overdose.” For several of CU Toxicology’s clients, the test has had a significant impact: The test has vastly improved Kaiser Permanente Colorado’s pain management and chemical dependency screening process by providing results that are far more detailed and useful to itsphysicians.

2. According to Charles Park, MD, a psychiatrist at several Denver-based methadone clinics and owner of his own addiction treatment center, CU Toxicology has helped him discover significantdrug use he did not expect to see and would not have known to ask for in confirmation tests. By employing CU Toxicology’s urine drug test, the practitioners at the Chronic Opiates Clinic at theUniversity of Colorado Hospital were able to precisely identify positive amounts of cocaine at lowerconcentration levels that were missed using standard drug screens. Urine drug testing is a standard practice in a variety of treatment settings, including addictiontreatment, pain management and employment assessment to verify patient compliance withprescribed medication and to detect misuse of prescription or illicit substances. “Treatment professionals simply cannot afford to miss multiple drug use in their patients—thestakes are too high,” said Dr. Galinkin. “CU Toxicology’s drug test is the first in the industry thatallows treatment professionals to treat with an accurate, complete picture of drug use. It takesthe guesswork out of the process.” CU Toxicology has developed a white paper, “Flying Blind. Traditional UDT: Irrelevant In a Polypharmacy World,” which highlights the reasons traditional urine drug screen technology hasbecome increasingly irrelevant and unreliable as rates of polypharmacy have risen. The whitepaper is available for download at www.cutoxicology.org/white_paper. CU Toxicology is a non-profit public/private enterprise of the University of Colorado School of Medicine. Using proprietary technology developed in the School of Medicine’s Department of Anesthesiology, CU Toxicology offers urine drug testing services to addiction treatment facilities,pain management centers, emergency departments and other medical and clinical settings thatrequire accurate, complete results. About CU Toxicology: CU Toxicology’s urine drug test identifies significantly more polypharmacy than standard screens, taking the guesswork out of drug use and misuse. Using revolutionary complete drugdiscovery technology that was developed at the University of Colorado School of Medicine, CUToxicology measures and confirms the presence of more than 500 prescription, illegal and over-the-counter drugs. CU Toxicology is a non-profit national reference laboratory that is CAP/CLIAaccredited and HIPAA compliant. Visit www.cutoxicology.org for more information. About the University of Colorado School of Medicine: Faculty at the University Of Colorado School Of Medicine work to advance science and improve care. These faculty members include physicians, educators and scientists at University of ColoradoHospital, Children’s Hospital Colorado, Denver Health, National Jewish Health, and the DenverVeterans Affairs Medical Center. The school is located on the Anschutz Medical Campus, one offour campuses in the University of Colorado system. To learn more about the medical school’scare, education, research and community engagement, please visit its web site. For additionalnews and information, please visit the University of Colorado Denver newsroom. Contact: Molly Koch Communications Strategy Group3225 East 2nd Avenue Denver, CO 80206303-433-7020 mkoch@csg-pr.com http://www.csg-pr.com ###