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Blood components review. What type of cell do you have the most of in your blood? What is the function of platelets? What 2 gases do RBCs carry? The decreased oxygen carrying capacity of erythrocytes is called _____. BLOOD GROUPS. DON’T COPY. DON’T COPY. Population group O A B AB Rh+
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Blood components review • What type of cell do you have the most of in your blood? • What is the function of platelets? • What 2 gases do RBCs carry? • The decreased oxygen carrying capacity of erythrocytes is called _____.
DON’T COPY Population group O A B AB Rh+ European-American 45 40 11 4 85 African-American 49 27 20 4 95 Korean-American 32 28 30 10 100 Japanese-American 31 38 21 10 100 Chinese-American 42 27 25 6 100 Native American 79 16 4 1 100
Blood types • ABO and Rh • antigens (agglutinogens) - proteins on surface of erythrocytes – determine type
ABO blood groups • Antigen A and antigen B • O IS THE ABSENCE OF ANTIGENS • Antibodies are the opposite (located in plasma) • EX: type A blood has type A antigen and antibodies for B (anti-B antibodies) • Type AB blood has type A and type B antigens and antibodies against neither • Too large to cross placenta
RH blood groups • an antigen • Have it (+) or don’t (-) • Do not develop antibodies automatically; need exposure first. 1st exposure = no transfusion reaction
Transfusion reactions • Antibodies bind to antigens of donor = agglutination, RBCs rupture and hemoglobin leaks out clogging kidneys leading to kidney failure
Hemolytic disease of the newborn (erythroblastosis fetalis) • Rh – mother • Rh+ fetus blood leaks into mother’s circulation, the mother develops anti-Rh antibodies (if she is Rh--). • Antibodies attack fetus’ blood: anemia, heart failure, death • Prevention: RhoGAM (prevent mother forming antibodies) in Rh- mothers after every birth