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Exploring Central Dogma: Protein Functions and DNA Mutations

Uncover the central dogma of biology and explore protein functions, codon base pairing rules, amino acid abbreviations, and DNA mutations through interactive activities in this educational workbook.

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Exploring Central Dogma: Protein Functions and DNA Mutations

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  1. Cover Page – Box 1 • Draw the Central Dogma of Biology picture in Box 1 of your cover page • Using you notebook, look up Proteins in your biomolecules unit. Identify: • A few functions of protein • The monomer of protein Box 1 Functions: Monomer:

  2. Cover Page – Box 2 • Glue in the picture in Box 2 • Using the picture, how many nitrogen bases make up a codon? • Using the picture, develop base pairing rules for the nitrogen bases between a DNA strand and the mRNA strand Box 2 How many nitrogen bases make a codon? DNA/RNA Base Pairing Rules

  3. Cover Page – Box 3 • Glue in the picture of a codon chart in Box 3 • Using the codon chart, find the abbreviation for the amino acid that corresponds to the codon (3 nitrogen base sequence) • Match the codon to the amino acid • UUC - ___________________ • AGU - ___________________ • ACU - ___________________ • GUG - ___________________ • CCC - ___________________ Box 3 Match the codon to the amino acid UUC - ___________________ AGU - ___________________ ACU - ___________________ GUG - ___________________ CCC - ___________________

  4. Cover Page – Box 4 • Glue in the table in Box 4 (you might have to turn it sideways • Read the brief description of the 3 different types of mutations • Using the original DNA sequence, mutate (or change) the DNA sequence as described. You can switch/insert/delete any nitrogen base that you want Box 4

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