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Pathogens and Infection. Origin. Disease and death were not always a part of this world Genesis 1:31 As a result of the Fall of man, sin caused a host of degenerative changes in the biological realm including disorders, diseases, aging, and death
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Origin • Disease and death were not always a part of this world • Genesis 1:31 • As a result of the Fall of man, sin caused a host of degenerative changes in the biological realm including disorders, diseases, aging, and death • However, God uses afflictions to accomplish His purposes in the lives of men
Disease • Does not allow the body to function normally • Can affect individual organs or an entire body system • Divided into two groups: • infectious • non-infectious
Infectious Disease • Infectious disease is a disease that can be passed from organism to organism • Caused by tiny organisms called PATHOGENS
Pathogens • Bacteria • Viruses • Fungi • Protist • Some worms
Pathogens come from… • Other people!
Pathogens come from… • Contaminated objects
Pathogens come from… • Animal Bites
Pathogens come from… • Our environment
Entry into Host • Pathogens have many different places on our body in which they can come in: • Skin • Orifices • Ears • Eyes • Noses • Any opening to the inside of our body
Infection • Infection– the ability of an organism or virus to enter, survive and multiply in a host and start symptoms • It works by damaging individual cells within the organs • In some cases it attacks an entire body system
Infection 1. Production of poisons, such as toxinsand enzymes, that destroy cells and tissues. 2. Direct invasion and destruction of host cells. • Triggering responses from the host’s immune system leading to disease signs and symptoms: • Swelling • Fever • Vomiting/diarrhea
Types of Infection • Types of Infection: • Bacterial infections • Viral infections • Fungal infections • Parasitic infections
Defense! • Happily, not all is lost! • Our bodies are equipped to prevent or stop most infections from occurring • First line of defense • Skin • Mucous • hygiene
Defense! • Second line of defense! IMMUNE SYSTEM!!! • The second line of defense is a group of cells, tissues, and organs that work together to protect the body. This is the immune system.
Defense! • Sometimes our bodies need some help getting rid of pesky pathogens • Antibiotics (“against life”) • Antiviral drugs • Steroids • Antihistamines
Defense! • Third line of defense… IMMUNITY! • After our immune system has successful pwned (defeated) pathogens, it will develop ANTIBODIESor markers that will alert the immune system if those pathogens ever show up again! Antibodies
Defense! - Vaccines • Dr. Edward Jenner, an English physician and scientist discovered that if people were given a similar but non-virulent strain of a disease they would have protection from the more deadly version • He called this weakened or similar version of the pathogen a vaccine • It allowed the patient to develop immunity without getting a case of the disease
Non-Infectious Diseases • Not caused by pathogens in the body • Not spread from organism to organism • Non-infectious Diseases are caused by malfunctions in the body. • Heredity • The environment • Lifestyle choices
Non-Infectious Disease • Cancer • Diabetes I and II • Genetic diseases • Cystic Fibrosis • Asthma • Allergies
Allergies • Allergiesare an abnormal response by the immune system to normally harmless substances • Ex: food, pollen, mold, dust, animals • An allergic reaction occurs when a allergenenters the body and the immune GOES CRAZY thinking it is a potentially life-threatening pathogen
Allergies • The immune system will go through a series of reactions and releases HISTIDINE, a chemical which causes many allergy symptoms: • Sneezing • Coughing • Itching • Rash/hives • Swelling • Watery eyes/nose
What causes allergies??? • “Hygiene Hypothesis” • Developed countries like the US and Europe have more people who suffer from allergies than life-threatening diseases like parasitic worm infections, smallpox, viral outbreaks • This hypothesis says that with improvements in sanitation, health care, and hygiene, we are reducing or even eliminating our exposure to many microbes and parasites immune systems are responding to SOMETHING (allergens) in order to keep itself ready
What did we learn?!? Pathogens and Disease Non-Infectious Disease and Allergies