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Essential Tremor and Parkinson’s Disease. Part 5 of 7. ET: Overlap with PD. ET and PD are among the most common movement disorders ET is considered the most prevalent movement disorder in the U.S. ET/PD: Pathophysiological relationship not established
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Essential Tremor and Parkinson’s Disease Part 5 of 7
ET: Overlap with PD • ET and PD are among the most common movement disorders • ET is considered the most prevalent movement disorder in the U.S. • ET/PD: Pathophysiological relationship not established • 2% to 19% of ET patients report parkinsonism www.wemove.org
ET: Overlap with PD • 10% of ET patients have a positive family history of PD • PD more common in ET and kindreds than otherwise expected: Geraghty and Jankovic (1985). Lang (1986). Koller (1994). • ET patient may develop striatonigral deficiency: Lee (1999). Farrer et al. (1999). www.wemove.org
ET and PD:Epidemiologic Investigations • Possible association: • Hornabrook and Nagurney (1976) • Jankovic and Geraghty (1985) • Jankovic et al. (1995) www.wemove.org
PD and ET www.wemove.org
PD and ET www.wemove.org
Tremor Due to PD and ET www.wemove.org