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Actinomyces and Nocardia

Actinomyces and Nocardia. Chapter 24. 教学大纲. 掌握：放线菌属的形态染色、硫磺样颗粒。 熟悉：放线菌的致病性、与龋齿和牙周炎关系。. Actinomyces. A. israeli, A. naeslundii; G ＋ Anaerobic , form filament, Exhibit true branching Related to decay tooth and peridentitis. Clinical specimens : Actinomycosis-pus.

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Actinomyces and Nocardia

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  1. Actinomyces and Nocardia Chapter 24

  2. 教学大纲 • 掌握：放线菌属的形态染色、硫磺样颗粒。 • 熟悉：放线菌的致病性、与龋齿和牙周炎关系。

  3. Actinomyces • A. israeli, A. naeslundii; • G＋ • Anaerobic, form filament, Exhibit true branching • Related to decay tooth and peridentitis

  4. Clinical specimens : Actinomycosis-pus Sulfur granule is visible

  5. Sections or tabletting : chrysanthemum-like appearance

  6. Opportunist organism, component of oral flora (endogenous) Take advantage of injury topenetrate mucosal barriers Trauma Surgery

  7. Actinomycosis • A chronic suppurative and granulomatous disease of the cervico-facial, thoracic or abdominal areas

  8. Pus contains "Sulfur Granules" • yellow – orange • Composed of mineralized “mycelial” mass • Colony of bacteria

  9. sulfur granule • Form burrowing sinus tracts to skin or mucus membranes—— • Discharge purulent material

  10. Pulmonary Actinomycosis

  11. nocardia Nocardiosis • G+, rod ，weakly acid-fast • N. asteroides; N. brasiliensis • Subcutaneous infections, pulmonary infections, and brain abscesses

  12. Subcutaneous infections pulmonary infections

  13. Mycetoma(足分枝菌病）

  14. Features of actinomycetes Actinomyces:branching bacilli, non-acid fastness, anaerobic, oral ,intestinal ,endogenous flora, chronic cellulitis, draining sinuses Nocardia: branching bacilli ,weak acid fast, aerobic, soil (exogenous ) , pseumonia ,skin pustules , brain abscess

  15. summary • Actinomyces :stain ,clinical feature, disease • Nocardia: stain, disease

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