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Suppl. B. NH-12 cells. YT-nu cells. ShcC RNAi. Li C R1 R2. Li C R1 R2. ShcC. P-Erk1/2. Erk1/2. a- tubulin. Serum (-) for 24 h. Effect of ShcC knockdown on ERK1/2 activation of NH12 and YT-nu neuroblastoma cells expressing ShcC.
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Suppl. B NH-12 cells YT-nu cells ShcC RNAi Li C R1 R2 Li C R1 R2 ShcC P-Erk1/2 Erk1/2 a-tubulin Serum (-) for 24 h Effect of ShcC knockdown on ERK1/2 activation of NH12 and YT-nu neuroblastoma cells expressing ShcC. Activation of Erk was examined in the cells other than TNB-1 cells which expresses ShcC. In NH-12 cells and YT-nu cells, elevation in the levels of activated Erk was recognized following downregulation of ShcC.