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THE CARDIOVASCULAR SYSTEM An In-depth Look MARK H. HYMAN, MD, FACP, FAADEP. THE CARDIOVASCULAR SYSTEM Chapter 3-Heart and Aorta Chapter 4-Systemic and Pulmonary Arteries. THE CARDIOVASCULAR SYSTEM Chapter 3-Heart and Aorta. NYHA Functional Classifications (Table 3-1, pg 26).
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THE CARDIOVASCULAR SYSTEMAn In-depth LookMARK H. HYMAN, MD, FACP, FAADEP
THE CARDIOVASCULAR SYSTEMChapter 3-Heart and AortaChapter 4-Systemic and Pulmonary Arteries
NYHA Functional Classifications (Table 3-1, pg 26) 1 - Ordinary Activity - No Symptoms 2 - Greater than Ordinary Activity Symptoms - Fatigue, Angina 3 - Comfortable At Rest Symptoms - Ordinary Activity 4 - Symptoms At Rest and Worse with Ordinary Activity
Evaluation of CAD • Exercise - treadmill or bicycle • Thallium Exercise Study • Exercise Wall Motion - Multi-gated • Exercise Echocardiography • Magnetic Resonance Study • Positron Emission • Coronary Angiography
Sensitivity and Specificity of Exercise Tests Test Sensitivity Specificity Stress ECG 68% 77% Spect Thallium-201 90 89 Tc-99 Sestamibi 89 90 Dipyridamole Thallium 85 87 Stress Echo 80 90
Stress Testing • Peak Level - METs • Symptoms and Signs • Arrhythmias • ST Changes • Blood Pressure
MET - Metabolic Unit • 1 MET = Energy Expenditure of Sitting at Rest • 3.5 cc/Kg/Min • Use Table 3-2 or 3-3 to convert exercise performance into METs.
3.2-Valve Stenosis - Aortic Impairment Valve Gradient Valve Area mm Hg CM2 Aortic Valve Mild < 25 > 1.5 Moderate 25 - 50 1.0 – 1.5 Severe > 50 < 1.0
3.2-Valve Stenosis - Mitral Impairment Valve Gradient Valve Area mm Hg CM2 Mitral Valve Mild < 5 > 1.5 Moderate 5 - 10 1.0 – 1.5 Severe > 10 < 1.0
Occupational Categories Carpentry 3.5 METs Maid 2.5 Plumbing 3.5 Farming 8.0 Forestry 17.0 Machine Tool 8.0 Shoe Repair 2.5 Typing 1.5
Problem With Categories • Average energy • Peak much higher • Travel exertion • No study on CAD • Time of work
Haskell Work Classification METs Activity Very Heavy > 6 Climb stairs Medium 4 - 6 50 lbs Light 2 - 4 20 lbs Sedentary < 2 Sit
Impairment VO2MAX MET Impairment > 25 > 7 None 20 - 25 5 - 7 Mild to Mod. 15 - 20 2.5 - 5 Severe < 15 < 2.5 Total
Cardiac Guidelines Peak METs Work Preclusion > 9 None to No Very Heavy Lifting 7 - 9 No Heavy Work 5 - 7 To Light Work 2.5 - 5 To Sedentary Work < 2.5 Total 1998 - California
Sustained Work - Percent of Maximal Level Achieved Ilmarinin, 1984 30 - 50% Astrand, 1988 40 - 45% NIOSH Guide 33% NIOSH Safety Manual 40 - 50%
Sustained Work During 8 Hour Day With Breaks Is 40% of Maximum MET Level
Maximum Short Term Work • Less than 15 minutes • Once to twice a day • 80% of maximal MET level achieved OR • 1-3 minutes maximum MET level achieved
AMA Impairment Classification for CHD Class Impairment Class I 0 - 9% Class II 10 - 29% Class III 30 - 49% Class IV 50 - 100%
CAD - Class 1: 0-9% • Equivocal History • < 50% Blockage • EB Scan Positive
CAD - Class 2: 10-29% • Functional Class I • On Treatment • Treadmill Neg > 7 METs • Post-CABG, Angioplasty and > 7 METs
CAD - Class 3: 30-49% • Symptoms of CAD • > 50% Blockage • 5 - 7 METs
CAD - Class 4: 50-100% • Functional Class 3 - 4 • < 5 METs
3.4 Congenital Heart Disease • Uses NYHA Functional Class Table 3-1 • Classification by degree of valve abnormality, heart failure, severity of pulmonary –systemic flow abnormality, degree of shunting
Congenital Heart Disease Common Examples • ASD/VSD • Ebsteins Anomaly • Tetrology of Fallot • Transposition of Great Vessels • Eisenmengers Complex
3.5 Cardiomyopathy • Table 3-9 Uses NYHA Functional Class and Treatment. Mets Not Used • However, it would be better if you use more objective criteria of EF and METS. See e.g. past California guidelines or SSA Guides.
3.6 Pericardial Heart Disease • Make sure at MMI as these can relapse and recur • If recurrent, demonstrate abnormality (echo, CT) • Table 3-10 Uses NYHA Functional Class and Treatment. Mets Not Used • However, again, it would be better if you use more objective criteria of EF and METS.
3.7 Arrhythmia • Impairment from arrhythmia must be combined with impairment of underlying heart disease if present
Arrhythmia Impairment AMA Guides I - Asymptomatic, Documented Arrhythmia Not Malignant, No Organic Heart Disease II - Asymptomatic, Documented Arrhythmia, Need Dietary Adjustment, Medication, Organic Heart Disease is Present III - Symptoms With Treatment, Infrequent, Active Life IV - Constant Symptoms; NYHA Class 3-4
THE CARDIOVASCULAR SYSTEMChapter 4 – Systemic and Pulmonary Arteries
4.1 Hypertensive Cardiovascular Disease • This is primarily a numbers game
Hypertension - Class 1: 0-9% • Asymptomatic Stage 1 or 2 Without Medicationor • Normal BP with Medication and • No End-Organ Damage
Hypertension - Class 2: 10-29% • Abnormal Urine • But No Renal Impairment • Retinal Change • No Symptoms; Stage1 or 2 with meds
Hypertension - Class 3: 30-49% • Asymptomatic; Stage 3 with Meds • Renal Insufficiency or • LVH • No CHF
Hypertension – Class 4 50-100% • Stage 1-3 with Medication and • Renal Disease or • Hypertensive Cerebrovascular Damage or • LVH, CHF
Pulmonary Hypertension • Findings of Right Heart Failure • Pulmonary Artery Pressure • Class 1 40-50 mm Hg • Class 2 51-75 mmHg • Class 3 >75 mm Hg • Class 4 >76 mm Hg or functional class 3-4
4.2 Diseases of the Aorta • Functional Classification for Aortic Symptoms such as dyspnea, wheezing, cough • At risk or had surgery
4.4 Peripheral Vascular Disease- Upper Extremity • Claudication • Physical findings especially of edema or ulcerations • Finger-brachial indices • Amputation
4.4 Peripheral Vascular Disease- Lower Extremity • Claudication (distance) Do Claudication Treadmill Study • Physical findings especially of edema or ulcerations • Ankle-brachial indices are not mentioned but should be done • Amputation