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SPERMATOGENESIS

By Dr Samina Anjum. SPERMATOGENESIS. Male reproductive system. Internal structure of testis. The reproductive system of the male. Two major functions: Production of sperm To provide safe passage for spermatozoa. Migration of primordial germ cells (PGCs). Formation of Testis.

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SPERMATOGENESIS

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  1. By Dr Samina Anjum SPERMATOGENESIS

  2. Male reproductive system

  3. Internal structure of testis

  4. The reproductive system of the male Two major functions: • Production of sperm • To provide safe passage for spermatozoa

  5. Migration of primordial germ cells(PGCs)

  6. Formation of Testis • First 6 weeks after conception, the gonads of males and females are similar in appearance (Indifferent stage). • If PGCs cells – Y chromosome (SRY gene)

  7. SPERMATOGENESIS • Is the sequence of events by which spermatogonia are transformed into spermatozoa. • It begins at puberty.

  8. At Birth • PMGs are present in sex cords of testis PMGs

  9. Puberty • Sex cords acquire lumen & become seminiferous tubules • PMGs give rise to spermatogonial stem cells

  10. PHASES OF SPERMATOGENESIS • Spermatogonial Phase (Mitosis) • Spermatocyte Phase/Spermatocytosis (Meiosis) • Spermatid Phase (Spermiogenesis)

  11. PHASE I-Spermatogonial Phase

  12. PHASE II-SPERMATOCYTOSIS Spermatids

  13. PHASE II- MEOSIS • Prophase-22 days • Largest cell

  14. PHASE III-(SPERMIOGENESIS)

  15. SPERMATOGENESIS Spermatogonial Phase Spermatocyte phase Spermiogenesis phase Cytokinesis is incomplete

  16. SPERMIOGENESISThe series of changes resulting in the transformation of Spermatids into spermatozoa • Formation of acrosome • Condensation of nucleus • Formation of neck, middle piece & tail • Shedding of most of the cytoplasm

  17. Mature Human Spermatozoa • Entire process of spermatogenesis takes approx. 74 days or 2 months • Approx. 300 millions sperms are daily produced.

  18. Sertoli cells • Support • Protect • Nutrition • Phagocytosis • Regulate spermatogenesis

  19. Phagocytosis of cytoplasm by the Sertoli cells.

  20. Epididymis • Storage • Acquire motility

  21. Hormonal Regulation Of Male Reproductive Function

  22. THANK YOU

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