1 / 43

HEART-LUNG TRANSPLANTATION

HEART-LUNG TRANSPLANTATION. Overall. ISHLT. 2006. J Heart Lung Transplant 2006;25: 880-892. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR.

herrod-shaw
Download Presentation

HEART-LUNG TRANSPLANTATION

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HEART-LUNG TRANSPLANTATION Overall ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  2. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR NOTE: This figure includes only the heart-lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of heart-lung transplants worldwide has declined in recent years. ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  3. AVERAGE CENTER VOLUMEHeart-LungTransplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  4. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY CENTER VOLUMEHeart-Lung Transplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  5. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUMELung Transplants: January 1, 1998 - June 30, 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  6. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival (Transplants: January 1982 - June 2004) Half-life = 3.1 years Conditional Half-life = 8.7 years N=3,086 Survival (%) N alive at 18 years = 18 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  7. HEART-LUNG TRANSPLANTATION Adult Recipients ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  8. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS (1/1982-6/2005) “Other” includes cancer, LAM, OB, sarcoidosis, bronchiectasis ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  9. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS(Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  10. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS BY ERA “Other” includes OB (non-ReTX), Bronchiectasis, Sarcoidosis ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  11. ADULT HEART-LUNG TRANSPLANTATIONIndications By Year (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  12. ADULT HEART-LUNG TRANSPLANTATIONIndications By Year (Number) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  13. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients(Transplants: January 1982 - June 2004) Half-life = 3.5 years Conditional Half-life = 9.0 years N=2,496 Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  14. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients by Era(Transplants: January 1982 - June 2004) Half-life: 1982-1995 = 3.1 years; 1996-1999 = 3.6 years; 2000-6/2005 = 5 years Conditional Half-life: 1982-1995 = 8.9 years Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  15. ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  16. ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis Conditional on Survival to 1 Year(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  17. ADULT HEART-LUNG RECIPIENTS Functional Status of Surviving Recipients (Follow-ups: April 1994 – June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  18. ADULT HEART-LUNG RECIPIENTSEmployment Status of Surviving Recipients(Follow-ups: April 1994 – June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  19. ADULT HEART-LUNG RECIPIENTS: Rehospitalization Post-transplantof Surviving Recipients(Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  20. ADULT HEART-LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 through June 2005 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  21. ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2004) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  22. ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2004) Any Induction Polyclonal ALG/ATG OKT3 IL2R-antagonist ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  23. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2001 through June 2005 NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  24. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2005 NOTE: Different patients are analyzed in Year 1 and Year 5 ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  25. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  26. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  27. Freedom from Coronary Artery Vasculopathy For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  28. Freedom from Bronchiolitis Obliterans For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  29. Freedom from Severe Renal Dysfunction*For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2005) *Severe renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  30. MALIGNANCY POST-HEART-LUNG TRANSPLANT FOR ADULTSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  31. Freedom from MalignancyFor Adult Heart-Lung Recipients(Follow-ups: April 1994- June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  32. ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25: 880-892

  33. HEART-LUNG TRANSPLANTATION Pediatric Recipients ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  34. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNGRECIPIENTS (Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  35. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART-LUNG RECIPIENTS(Transplants: January 1982 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  36. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Year of Transplant Number of Transplants NOTE: This figure includes only the heart transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of pediatric heart-lung transplants worldwide has declined in recent years. ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  37. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Era of Transplant Percentage of Transplants ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  38. NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTS ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  39. “Other” includes Bronchiectasis, Alpha-1, and OB (non-ReTX) DIAGNOSIS IN PEDIATRIC HEART –LUNG TRANSPLANT RECIPIENTS (Age: 11-17 Years) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  40. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  41. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival(Transplants: January 1982 - June 2004) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  42. PEDIATRIC HEART-LUNG TRANSPLANTATION Kaplan-Meier Survival by Era(Transplants: January 1982 - June 2004) Survival (%) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

  43. PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2005) ISHLT 2006 J Heart Lung Transplant 2006;25:904-911

More Related