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HEART-LUNG TRANSPLANTATION

HEART-LUNG TRANSPLANTATION. Overall. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR. AVERAGE CENTER VOLUME Heart-Lung Transplants: January 1, 1998 - June 30, 2003. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUME Heart-Lung Transplants: January 1, 1998 - June 30, 2003.

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HEART-LUNG TRANSPLANTATION

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  1. HEART-LUNG TRANSPLANTATION Overall

  2. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR

  3. AVERAGE CENTER VOLUMEHeart-LungTransplants: January 1, 1998 - June 30, 2003

  4. DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUMEHeart-Lung Transplants: January 1, 1998 - June 30,2003

  5. HEART-LUNG TRANSPLANTATIONKaplan-Meier SURVIVAL (Transplants: January 1982 - June 2002) Half-life = 2.8 years Conditional Half-life = 8.3 years N=2,973 Survival (%)

  6. HEART-LUNG TRANSPLANTATION Adult Recipients

  7. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS (1/1982-6/2003) “Other” includes cancer, LAM, OB, sarcoidosis, bronchiectasis

  8. DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS(Transplants: January 1982 - June 2003)

  9. 1982-1995 1/1996-6/2003 DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS BY ERA “Other” includes OB (non-ReTX), Bronchiectasis, Sarcoidosis

  10. HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients(Transplants: January 1982 - June 2002) Half-life = 3.1 years Conditional Half-life = 8.8 years N=2,389 Survival (%)

  11. ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2002)

  12. ADULT HEART-LUNG RECIPIENTSFunctional Status (Follow-ups: April 1994 – June 2003)

  13. ADULT HEART-LUNG RECIPIENTSEmployment Status(Follow-ups: April 1994 – June 2003)

  14. ADULT HEART-LUNG RECIPIENTS: Rehospitalization Post-transplant(Follow-ups: April 1994 - June 2003)

  15. ADULT HEART-LUNG RECIPIENTS Induction ImmunosuppressionFor follow-ups between January 2001 through June 2003

  16. ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Follow-ups: January 2000 - June 2003)

  17. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2001 through June 2003 NOTE: Different patients are analyzed in Year 1 and Year 5

  18. ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2003 NOTE: Different patients are analyzed in Year 1 and Year 5

  19. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2003)

  20. POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2003)

  21. Freedom from CAV For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2003)

  22. Freedom from Bronchiolitis Obliterans For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2003)

  23. Freedom from Severe Renal Dysfunction*For Adult Heart-Lung Recipients(Follow-ups: April 1994-June 2003) *Severe renal dysfunction = Creatinine > 2.5 mg/dl, dialysis or renal transplant

  24. MALIGNANCY POST-HEART-LUNG TRANSPLANT FOR ADULTSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2003)

  25. Freedom from MalignancyFor Adult Heart-Lung Recipients(Follow-ups: April 1994- June 2003)

  26. ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2003)

  27. HEART-LUNG TRANSPLANTATION Pediatric Recipients

  28. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNGRECIPIENTS (Transplants: January 1982 - June 2003)

  29. AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART-LUNG RECIPIENTS(Transplants: January 1982 - June 2003)

  30. AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Year of Transplant Number of Transplants

  31. NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTS

  32. “Other” includes Alpha-1, Bronchiectasis, IPF and OB (non-ReTX) DIAGNOSIS IN PEDIATRIC HEART –LUNG TRANSPLANT RECIPIENTS (Age: 11-17 Years)

  33. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2002)

  34. PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival(Transplants: January 1982 - June 2002) 1-10 years vs. 11-17 years p = 0.9

  35. PEDIATRIC HEART-LUNG TRANSPLANTATION Kaplan-Meier Survival by Era(Transplants: January 1982 - June 2002) Survival (%)

  36. PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2003)

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