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Respiratory Effects of Pesticide Exposure

Respiratory Effects of Pesticide Exposure. Pesticide Health Effects Medical Education Database (PHEMED). Acute Symptoms. Upper respiratory irritation Rhinitis Scratchy throat Cough Sneezing Runny nose Pulmonary edema Pulmonary consolidation Dyspnea. Naphthalene Paraquat

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Respiratory Effects of Pesticide Exposure

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  1. Respiratory Effects of Pesticide Exposure Pesticide Health Effects Medical Education Database (PHEMED)

  2. Acute Symptoms • Upper respiratory irritation • Rhinitis • Scratchy throat • Cough • Sneezing • Runny nose • Pulmonary edema • Pulmonary consolidation • Dyspnea

  3. Naphthalene Paraquat Chloropicrin Acrolein Dichloropropene Ethylene dibromide Sulfur dioxide Sulfuryl fluoride Acrylonitrile Formaldehyde Cadmium dusts ANTU Upper Respiratory Irritation

  4. Sneezing & Runny Nose • Sneezing - Sabadilla • Runny nose • Pyrethrins • Inorganic arsenicals • Organophosphates insecticides • Carbamate insecticides

  5. Methyl bromide Phosphine Phosphorus Phosphine Ethylene oxide Ethylene dibromide Acrolein Pyrethiods Sulfur dioxide Cationic detergents Creosote Methylisothiocyanate Cadmium Pulmonary Edema Many chemicals come with a hydrocarbon vehicle, well known to cause pulmonary edema

  6. Pulmonary Consolidation • Paraquat - fibrosis • Cadmium dusts • Methyl bromide secure.hosting.vt.edu

  7. Nicotine Paraquat ANTU Cadmium dusts Cyanamide Sulfuryl fluoride Pentachlorophenol Methyl bromide Sulfur dioxide Chloropicrin Dyspnea

  8. Other Respiratory Problems • Only a few pesticides are ‘sensitizers’ causing allergic reactions along with OTHER triggers • dusts, pollens, animals, diesel, molds, grains, hay, disinfectants • Organophosphates and carbamates inhibit cholinesterase resulting in • Constriction of the bronchial tubes • Increased secretions • Difficulty in breathing

  9. Chronic Respiratory Problems • Insecticide related wheezing with*: • parathion (NR) • Chlorpyriphos (Lorsban/Dursban) • malathion (MAXIDE) • Herbicide related wheezing with*: • paraquat • Atrazine (Shotgun…95 labels) • Alachlor (Lasso) • chlorimuron ethyl (NR) • EPTC (EPTAM, ERADICANE) *Source: Hoppin JA et al (2006). Pesticides and Adult Respiratory Outcomes in the Agricultural Health Study. Ann. New York Academy of Sciences. 1076:343-354.

  10. Chronic Bronchitis in Farm Women and Pesticides • Controlling for: • Smoking • 2nd hand smoke • Asthma • Usual suspects: dust, solvents, manure Insecticides • Dichlorvos • DDT Herbicides • Cyanazine • Paraquat Fumigant • methyl bromide Source: Valcin M, et al. Chronic bronchitis among nonsmoking farm women in the agricultural health study. J Occup Environ Med. 2007 May;49(5):574-83.

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