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Equine Vaccines. Marissa Kazeck. Core vs. Non-core. Core : vaccines that every animal of that species should receive. Protect against the most dangerous diseases. Tetanus, Eastern/Western Equine Encephalomyelitis, West Nile Virus, and Rabies
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Equine Vaccines Marissa Kazeck
Core vs. Non-core • Core: vaccines that every animal of that species should receive. Protect against the most dangerous diseases. • Tetanus, Eastern/Western Equine Encephalomyelitis, West Nile Virus, and Rabies • Non-core: vaccines an animal should receive depending on its particular lifestyle. • Strangles
Tetanus • Transmission: Tetanus can happen when a horses wound becomes infected with the bacterial spore of Clostridium tetani. The spores multiply and produce a powerful poison that affects the muscles. • Clinical Signs: stiff legged gait, tail held stiffly, ears pricked forward, horse may fall • Outcome: treatment is difficult, and often unsuccessful. • Zoonotic potential: Ears pricked forward Tail held stiffly Paralysis of breathing muscles Stiff legged gait
Tetanus cont… • Route given: intramuscularly (IM). Best spot for that is the side of the neck. • Vaccine Schedule: • Adult previously vaccinated: Vaccinate annually. • Adult previously unvaccinated: Give a primary 2 dose series within a 4 to 6 week interval between doses. Then vaccinate annually. • Pregnant previously vaccinated: Vaccinated annually and 4 to 6 weeks before foaling. • Pregnant previously unvaccinated: Give a 2- dose primary series with a 4 to 6 week interval between doses. Revaccinated 4 to 6 weeks before foaling. • Foals of mares vaccinated: Give a primary 3 dose series beginning at 4 to 6 months of age. 4 to 6 week interval between first and second does, third dose should be given at 10 to 12 months of age. • Foals of mares unvaccinated: Give a primary 3 dose series beginning at 1 to 4 months of age with 4 week intervals between doses. • All horses should be vaccinated annually.
Eastern/Western EquineEncephalomyelitis • Transmission: By mosquitoes, and sometimes other bloodsucking insects. Horse from wild birds or rodents. • Clinic Signs: Altered mentation, impaired vision, wondering, head pressing, circling, inability to swallow, irregular gait, paresis and paralysis, convulsions, and death. • Outcome: No specific therapy. Supportive care includes fluids for the horse (unable to drink), use of anti-inflammatory agents, and anticonvulsants. Good nursing care. • Zoonotic potential: People may be infected. Should always be aware of the possibility of human infection and take precautions.
Eastern/Western EquineEncephalomyelitis cont… • Route given: intramuscularly (IM). Best spot for that is the side of the neck. • Vaccine Schedule: • Adults previously vaccinated: Annual revaccination (best in spring) • Adults previously unvaccinated: Give primary series of 2 doses with a 4 to 6 week interval between doses. Then annually. • Pregnant previously vaccinated: Vaccinated 4 to 6 weeks before foaling. • Pregnant previously unvaccinated: Give a 2 dose primary series with a 4 week interval between doses. Booster again 4 to 6 weeks before foaling. • Foals of vaccinated mares: Give a primary 3 dose series starting at 4 to 6 months of age, with a 4 to 6 week interval between the first and second dose. The third dose should be given at 10 to 12 months of age. • Foals of unvaccinated mares: Give a primary 3 dose series starting at 3 to 4 months of age, with a 4 week interval between first and second dose. The third dose should be given at 10 to 12 months of age. • All horses should be vaccinated annually.
West Nile Virus • Transmission: Mosquitoes (they feed off wild birds). • Clinical signs: Weakness/Paralysis of hind limbs,impaired vision, circling, wondering, convulsions, colic, change in behavior, and restlessness. • Outcome: No specific treatment. Supportive care (IV fluids), death is possibility if not treated the correct way or fast enough action taken. • Zoonotic Potential: People may get it from being bit from an infected mosquito (rare to happen). Veterinarians should take precautions with birds.
West Nile Virus cont… • Route given: intramuscularly (IM). Best spot for that is the side of the neck • Vaccine Schedule: • Adult previously vaccinated: Annual revaccination before threat of mosquitoes. • Adult previously unvaccinated: Give a primary 2 dose series with 4 to 6 week intervals between the doses. Then annually. • Pregnant previously vaccinated: Vaccinated 4 to 6 weeks before foaling. • Pregnant previously unvaccinated: Same as Adult previously vaccinated, then again 4 to 6 weeks before foaling. • Foals of vaccinated mares: Give a primary 3 dose series starting at 4 to 6 months of age with a 4 to 6 week interval between first and second dose. The third dose should be given at 10 to 12 months of age. • Foals of unvaccinated mares: Give a primary 3 dose series with a 30 day interval between first and second doses and a 60 day interval between second and third doses. • All horses should be vaccinated annually.
Rabies • Transmission: Occurs through a bite of an infected animal (usually wildlife). Bites on horses occur mostly on the muzzle, face, and lower limbs. • Clinical signs: Signs may vary between horse. Some possible signs include, depression, loss of appetite, excessive salivation, difficulty swallowing, lack of coordination, aggressive, colic, convulsions, and paralysis. • Outcome: Death usually occurs within 3 to 5 days after clinic signs are noticed. • Zoonotic potential: No documented cases of horse to human transmission, but it can happen. All precautions should be taken.
Rabies cont… • Route given: intramuscularly (IM). Best spot for that is the side of the neck • Vaccine schedule: • Adult previously vaccinated: Annual revaccination • Adult previously unvaccinated: Give a single primary dose. Revaccinate annually. • Pregnant previously vaccinated: Vaccinated 4 to 6 weeks before foaling. • Pregnant previously unvaccinated: Vaccinated 4 to 6 weeks before foaling. • Foals of vaccinated mares: Give a primary dose series. First dose given no earlier than 6 months of age. Second dose given 4 to 6 weeks later. • Foals of unvaccinated mares: First dose should be given at 3 to 4 months of age. • Vaccinated all horses annually.
References • http://www.cyberhorse.net.au/csl/tetanus.htm • http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/100900.htm • http://www.aaep.org/vaccination_guidelines.htm • http://www.cvm.msu.edu/alumni-friends/information-for-animal-owners/rabies-in-horses/