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What is the differential diagnosis of acute UGIB?. What is the differential diagnosis of acute UGIB? Peptic Ulcer Disease Gastroesophageal Varices Mallory-Weiss tears Stress Gastritits Esophageal, gastric, duodenal tumors Stress gastritis Esophagitis Angiodysplasia Aortoduodenal fistula
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What is the differential diagnosis of acute UGIB? • Peptic Ulcer Disease • Gastroesophageal Varices • Mallory-Weiss tears • Stress Gastritits • Esophageal, gastric, duodenal tumors • Stress gastritis • Esophagitis • Angiodysplasia • Aortoduodenal fistula • Pancreatitis induced pseudoaneurysm
What percentage of acute GI hemorrhage is of “upper” origin (meaning stomach, esophagus or duodenum)? • What about from the small bowel?
What percentage of acute GI hemorrhage is of “upper” origin (meaning stomach, esophagus or duodenum)? • 80% • What about from the small bowel? • 1%
In the setting of UGIB from PUD, which 3 factors were most predictive of rebleeding?
In the setting of UGIB from PUD, which 3 factors were most predictive of rebleeding? • Hypovolemic shock during EGD • Ulcer(s) > 2 cm across • Forrest type I or II lesions on EGD
Which subsets of SICU patients are at greatest risk for stress gastritis (4 subsets)?
Which subsets of SICU patients are at greatest risk for stress gastritis (4 subsets)? • Major burns • Trauma • Sepsis • Coagulopathy with respiratory insufficiency (at greatest risk)
List the Forrest Classification of Endoscopic Appearance of Bleeding Ulcers:
List the Forrest Classification of Endoscopic Appearance of Bleeding Ulcers: • Ia spurting bleeding • Ib non-spurting but active bleeding • IIa visible vessel • IIb non-bleeding ulcer with overlying clot • IIc ulcer with black base (hematin) • III clean ulcer base