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Models of HIV Infection at the Immune System Level

Models of HIV Infection at the Immune System Level. Douglas E. Norton Villanova University. Mellon Tri-Co Faculty Modeling Working Group Bryn Mawr College December 12, 2003. Villanova Summer. Research Institute.

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Models of HIV Infection at the Immune System Level

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  1. Models of HIV Infection at the Immune System Level Douglas E. Norton Villanova University Mellon Tri-Co Faculty Modeling Working Group Bryn Mawr College December 12, 2003

  2. Villanova Summer Research Institute

  3. The National Health and Nutrition Examination Survey is a survey conducted by the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention. This survey has been designed to collect information about the health and diet of people in the United States. http://www.cdc.gov/nchs/nhanes.htm

  4. b, m bo m0 N

  5. EQUILIBRIUM POINT b, m bo m0 N

  6. EXAMPLE: Rabbits and sheep compete for a limited amount of grass. We assume logistic growth for each, that rabbits reproduce rapidly, and that the sheep can crowd out the rabbits. Then some unrealistic coefficients (just to make this example look friendlier) and these assumptions could give the following model: dx/dt = x(3 ­– x – 2y) dy/dt = y(2 ­– x – y), where x(t) = size of the rabbit population and y(t) = size of the sheep population. This is an example of what the N1 – N2 system may look like, algebraically speaking, if multiplication and constant renaming are utilized. We can explore this model with a natural extension of our recipe to find equilibrium points and possible extinction of one population.

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