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Mendelian Genetics Review. Gregor Mendel- “the father of genetics” Used pea plants because of their relative simplicity and short reproductive cycle. Why do certain traits disappear in one generation and reappear in the next? “ elementen ”. Mendel’s Laws.
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Gregor Mendel- “the father of genetics” • Used pea plants because of their relative simplicity and short reproductive cycle. • Why do certain traits disappear in one generation and reappear in the next? • “elementen”
Mendel’s Laws • Paired genes will separate from one another during gamete formation • As long as genes are not linked, that is they are found on separate chromosomes, the inheritance of one gene will not guarantee the inheritance of another.
Dominant vs. recessive alleles • 1 initial for a gene • Capital domiant, lowercase recessive • P, F1, F2 generations • True-breeding
Diploid organisms have 2 sets of chromosomes- one maternal, one paternal • 2 alleles for every trait
Monohybrid Punnett Square Letters on the outside represent possible alleles in the gametes (haploid) Letters in the boxes represent possible gene combinations of individuals in a new generation (diploid)
Genotype- • Phenotype- • Pay attention for what is being asked for and do not give the opposite! • 3 possibilities for genotype: • Homozygous dominant, Heterozygous, Homozygous recessive
Wildtype vs. Mutant • Know how these terms relate to Punnett square problems. Can you use this information in your Punnett square?
Dihybrid Crosses • Looking at two traits simultaneously
Dihybrid steps to success! • Identify the genotypes of the parents • Identify the possible allele combinations in the gametes for each parent separately • Line up possible gametes along the punnett square. • Cross individuals You may not need to use all 16 squares!!
Example: • Parent 1: CCdd- gamete possibilities: Cd • Parent 2: CcDD- gamete possibilities: CD, cD • Cross: Cd CD cD
Ratios • Separate with colon ( : ) • Genotypic is a ratio of GENOTYPES • Common genotypic ratios for monohybrid crosses • 1:2:1 • 1:1 • 1
Ratios • Phenotypic is a ratio of PHENOTYPES • Common phenotypic ratios for monohybrid cross: • 3:1 • 1:1 • 1 Phenotypic ratio when heterozygous for all traits in a dihybrid cross: - 9:3:3:1 (Dom/Dom, Dom/Rec, Rec/Dom, Rec/Rec)
Probability • Expected/Total • Give as a fraction, decimal, or percent. • Two heterozygous purple flowers are crossed. What is the probability of having a white flower in their F1 generation? • ¼, or 0.25, or 25%
Product Rule • When dealing with more than one trait: • The probability of inheriting a combination of traits is the same as the product of the probability of inheriting each trait individually. Parent 1: AABbCc Parent 2: AaBbcc What is the probability of having an offspring that is heterozygous for all traits? AaBbCc ½ * ½ * ½ = 1/8
Vocabulary • Dominant • Recessive • Allele • Genotype • Phenotype • Homozygous • Heterozygous • True-breeding • Wildtype • Mutant • Gene • “Elementen” • P,F1,F2 generations • Genotypic ratio • Phenotypic ratio