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Proposal writing. By Dr. Hamda Qotba, B.Med.Sc, M.D, ABCM. What are the main components?. Title Introduction Rationale Aim Objectives Methodology Results Discussion Recommendations. Stages of research process. Selecting a problem Formulate hypothesis Reviewing the literature
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Proposal writing By Dr. Hamda Qotba, B.Med.Sc, M.D, ABCM Dr.Hamda Qotba
What are the main components? • Title • Introduction • Rationale • Aim • Objectives • Methodology • Results • Discussion • Recommendations Dr.Hamda Qotba
Stages of research process • Selecting a problem • Formulate hypothesis • Reviewing the literature • Constructing research design • Analysis of data • Generating conclusions • Writing proposal Dr.Hamda Qotba
Basic guidelines • Priority health problems • Simple, low cost, yield practical results • Influence policy, improve services, improvement of community health Dr.Hamda Qotba
How and what to select? • Relevance • Avoidance of duplication • Feasibility • Political acceptability • Applicability • Interest • Theoretical and practical value • Time frame Dr.Hamda Qotba
Title • Subject of study • Where? • When? Title Dr.Hamda Qotba
Introduction • Define the nature of the problem • Demographic background • Geographic sitting • Community size • Related health services • Information related to the study (literature review) • Rationale (purpose to carry out the study) • Aim (General) • Objectives • SMART Dr.Hamda Qotba
Methodology • Detailed like cook book • Achieve the objective • Follow Islamic teaching and moral ethics Dr.Hamda Qotba
Character of sample population Study type Sample size determination Sampling technique Case definition Selection and exclusion criteria Tools and source of data collection Validity and reliability Statistical methods Package and tests Pilot study When, where, and how? Limitations Methodology contents Dr.Hamda Qotba
study question study design study sample study variables pilot study data collection data analysis results and conclusion Dr.Hamda Qotba
Research question (FINER) • Feasible • Adequate number of subject, money • Interesting • Novel • To confirm or refute findings • Ethical • Relevant • To clinical or health policy, future research • Comparison • Risk factor • Association Dr.Hamda Qotba
Study design • Case series • Define a problem • Survey • Describe a population • Case- Control • Compare cases to controls • Cohort • Follow exposed subject • Randomized Clinical trial • Expose and follow Dr.Hamda Qotba
Subjects Population of interest Study sample • Inclusion criteria • Main characteristics of the population • Exclusion criteria • Individuals that complicate the study Dr.Hamda Qotba
Sampling strategies • Random sampling • Every individual has the same chance of being chosen • Systematic sampling • Every Nth individual is chosen • Stratified sampling • Population divided into subgroups (strata) and each subgroup randomly sampled Dr.Hamda Qotba
Sampling strategies • Cluster sampling • Population divided into subgroups and some of subgroup randomly selected then sampled • Convenience sampling • You take what you can get Dr.Hamda Qotba
How to select appropriate statistical test • Type of variables • Quantitative (blood pres.) • Qualitative (gender) • Type of research question • Association • Comparison • Risk factor • Data structure • Independent • Paired • matched Dr.Hamda Qotba
Types of variables • Quantitative • Continuous (age, blood pres.) • Discrete( number of brothers, years) • Qualitative • Categorical ( blood groups, gender) • Ordinal (educational level, stage of disease) Dr.Hamda Qotba
Types of variable Dependent independent Test categorical categorical chi-square Quantitative categorical Log. regression categorical 2 out come T test 3+out come ANOVA Quantitative Quantitative Quantitative Body of research question Association of 2 variable(dep, indep) Spearman Correlation linear Regression Dr.Hamda Qotba
Comparing (difference) variables Variable Number of independent variable 2 groups paired data >2groups ANOVA T test Paired T test Quantitative Ordinal Categorical Mann-Whitney Kruskal wallis Wilcoxon chi-square* McNemar chi-square • * When 1 of the cells have <5 in expected fischer exact • When 1 of the cells have <5 in observed yats correction Dr.Hamda Qotba
Looking for Risk Factor Types of variables Dependent several indepen. Test Multiple log. Regression categorical categorical quantitative categorical ANOVA quantitative quantitative Linear, log regression Dr.Hamda Qotba