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Survivin-Specific T Cell Inductions in Donors

Overview of survivin-specific T cell priming and restimulation per donor, including mRNA constructs, CD8+ T cells, APC used, and readout systems (tetramer/ELISpot). IL12 co-electroporated with survivin constructs except in donors 2 and 3, where IL21 was used.

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Survivin-Specific T Cell Inductions in Donors

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  1. Additional file 2: Table S1 Donor Additional file 1:Table S1 Overview of survivin specific T cell inductions per donor. Shown are the mRNA constructs, the number of CD8+ T cells, the antigen presenting cell (for initial priming and subsequent restimulation), and the readout systems (tetramer and/or ELIspot) used. Note: IL12 was co-electroprated with the survivin constructs accept in donors 2 and 3, where we co-electroporated IL21

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