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Plasmodium Vivax Malaria. Michala Wood Hour-3 11-29-11. How I received this awful sickness.
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Plasmodium VivaxMalaria Michala Wood Hour-3 11-29-11
How I received this awful sickness I had traveled down to Central and South America with a group of friends. It was all fun and games, but sometime between all of that I was bitten by Anopheles Mosquito, which I had no idea when it occurred. I notice I had a red bump that itched and assumed I was bitten by a mosquito, but it wasn’t a big deal. That happens all the time. Little did I know this little bug could ruin my whole trip.
Diagnosis I first started noticing something was wrong with me when I got the chills, fever, weakness, vomiting, and diarrhea. I would randomly get extremely hot, then I’d be extremely cold . I was no longer having any fun on this trip and felt bad for my friends having to worry about me. I finally realize this sickness wasn’t going to go away on its own, so I found a doctor nearby.
I told the doctor my symptoms he thought it could be the flu, but he told me he was going to check for malaria. I had no idea what that was and I knew I couldn’t possibly have that. He came back in with some kind of tool that pricked my finger and smeared my blood, two thick and thin streaks on a giemsa stain glass. When he came back he informed me I had Plasmodium Vivax. He showed me the stained glass where my chromatin in my RBC’s are large and my cytoplasm can become ameboid.
Treatment P. Vivax is normally treated with Chloroquine and Primaquine. They act against the liver reducing the chance of relapse. You take the appropriate amount of pills, by mouth, that your doctor prescribed. Unfortunately the parasite is becoming resistant to the treatment. Scientist are working on other treatments and possible vaccines to use against the parasite.
Intermediate: Mosquito Definitive: Human
Instars • Early trophozoite: • About ½ diameter of red cell; chromatin dot heave; vacuoles prominent • Growing trophozoite: • Pseudopodia common; one or more food vacuoles • Late trophozoite: • Large mass of chromatin; fine brown hemozoin; almost fills red cell • Hemozoin: • Short, delicate rods, irregularly scattered; yellowish brown • Appearance of erythrocyte: • Larger than normal often oddly shaped; Schuffner’s dots at all stages but young rings; multiple infection occasional • Schizont: • 12-24 merozoits; hemozoin in one or two clumps almost fills red cell • Microgametocyte's: • Rounded or oval; almost fill red cell; dark hemozoin throughout cytoplasm; chromatin diffuse, in large mass, pink; small amount of light blue cytoplasm; no vacuoles • Macro gametocytes: • Stains darker blue; chromatin more compact, dark red • EE cycle: • 8 days • Prepatent pd., minimum: • 11-13 days • Schizogonic cycle: • 48 hours • Developmental in mosquito: • 10 days at 25 degrees Celsius to 30 degrees Celsius