National Institutes of Health (NIH) Training Opportunities to Develop Scientists

1. National Institutes of Health (NIH) Training Opportunities to Develop Scientists Jane D. Scott, ScD, MSN, FAHA Director, Office of Research Training & Career Development Division of Cardiovascular Sciences National Heart, Lung, and Blood Institute National Institutes of Health Cleveland State University Colleges of Sciences and Health Professions April 11, 2013

2. Goals for today NIH’s role in research & research training Identify research training opportunities for individuals interested in pursuing a research career. Identify programs for PhDs and clinician scientists Provide links to NIH resources

3. National Institutes of Health The NIH is part of the U.S. Department of Health and Human Services (HHS).

4. National Institutes of Health The National Institutes of Health (NIH) is the largest source of funding for biomedical research in the world, making important medical discoveries that improve health and save lives.

5. What is Biomedical Research? Biomedical research advances knowledge in biology and medicine and related fields.

6. National Institutes of Health

7. NIH Funding: 27 Institutes and Centers

8. Most NIH Funds Are Spent Beyond Bethesda NIH Budget FY 2010: $30.759 B At NIH (intramural): $3.22 (11%) Outside NIH (extramural): $26.3 B (89%)

9. NIH Research FundingCleveland State University Today

10. NIH funding at Cleveland State University 5R01AG03954702CIRCADIAN CLOCK AND DIETARY RESTRICTIONKONDRATOV, ROMAN V CLEVELAND STATE UNIVERSITY 2012 NIA $291,100 5R01AI06609507CHARACTERIZE FUNCTIONS OF T. BRUCEI RAP1 AND TRF IN ANTIGENIC VARIATION AND TELOMLI, BIBO CLEVELAND STATE UNIVERSITY 2013 NIAID $319,500 5R01HL07916408TRANSLATIONAL SILENCING IN MONOCYTES: ROLE OF L13AMAZUMDER, BARSANJIT CLEVELAND STATE UNIVERSITY 2012 NHLBI $351,464 5R01HL10260404RECOMBINANT AND CHEMO-/BIO-ORTHOGONAL SYNTHESIS OF LIPOSOMAL THROMBOMODULINSUN, XUE-LONG CLEVELAND STATE UNIVERSITY 2013 NHLBI$284,675 1R01NS08171001RESTORING UPPER LIMB MOVEMENT SENSE TO AMPUTEES; A MOVE TOWARDS NATURAL CONTROL OMARASCO, PAUL CLEVELAND VA MEDICAL RESEARCH/ED/FDN 2012 NINDS OD $327,033

11. NIH funding at Cleveland State University 1R03CA15990601A1THE CONTEXT OF CAREGIVING AND BEREAVEMENT ADJUSTMENT IN LATE-STAGE CANCERFRANCIS, LINDA E CLEVELAND STATE UNIVERSITY 2012 NCI$71,000 1R15AI10388901DRUG DEVELOPMENT OF ORALLY ACTIVE ANTI-TRYPANOSOMIASIS AGENTSSU, BIN CLEVELAND STATE UNIVERSITY 2013 NIAID$436,500 1R15DK09271601FLUID FLOW MAY BE AN ENVIRONMENTAL MODIFIER OF ADPKD DISEASE PROGRESSIONRESNICK, ANDREW CLEVELAND STATE UNIVERSITY 2011 NIDDK$332,344 1R15GM09905601CONTROL OF PAIRING AND RECOMBINATION DURING MEIOSISBOERNER, VALENTIN CLEVELAND STATE UNIVERSITY 2011 NIGMS$284,000 1S10OD01038101NIKON A1RSI CONFOCAL MICROSCOPEBARIK, SAILEN CLEVELAND STATE UNIVERSITY 2012 OD $590,931

12. Are you interested in a research career?

13. Awards for individuals with a Health-Professional Doctorate • Mentored Patient-Oriented • Research CDA (K23)

14. NIH Research Training: 4 key programs Institutional T32 Training Programs for pre & post-docs Individual Fellowship Grants (F awards) Institutional Career Development Awards (K) Individual Career Development Awards

15. Research Training: T32

16. Research Training: T32

17. NIH Training (T) grants, Midwest356 programs for 101M

18. Fellowship Awards Individual pre and post doctoral awards Generally after T32 training 2-3 years of additional research F31 F32 F30

19. F31 Fellowship Please note, there can be big difference between NIH and Institute specific programs NHLBI F31 individual predoctoral fellowships are to Promote Diversity in Health Related Research For individuals with disabilities, or from underrepresented racial and ethnic groups, or individuals from disadvantaged backgrounds pursuing advanced degrees in biomedical and behavioral sciences. Up to 5 years support, must have US citizenship For pursuit of PhD or comparable degree

20. F32 Fellowship Individual award Postdoctoral support Up to 3 years full-time support Frequently transition from T32 to F32 Includes stipends, tuition and fees, more

21. F30 Fellowship Individual award Combined MD/PhD program Up to 6 years of support Only training award that supports tuition for medical school Citizenship required Extremely competitive award

22. Individual K Awards (early faculty):

23. Individual K awards:

24. K99/R00 grant Joint K/R program Mentored career development (K99) 2 years Independent research (R00) 3 years Must be a post-doc Rules are changing (<5 yrs chg to <4 yrs) Overwhelmingly utilized by PhDs No citizenship requirements Current discussion for broad expansion across NIH

25. NIH Diversity Supplement Awards Supplements are available for some research awards, & each institute different HS, undergrad, pre, post, early faculty Requested by the R01 Principal Investigator Supports the conduct of research by supplement awardees for 2-3 years. http://www.nhlbi.nih.gov/funding/training/guid-app.htm

26. NIH Loan Repayment Programs

27. NIH Loan Repayment Programs

28. Getting started:

29. Getting started:

30. RePORT & RePorter: http://report.nih.gov

31. Am Heart J 2011;161:13-67

32. Circ Res. 2012;110:910-914 K08 and K99 Cardiovascular Training : Comparisons and Trends Among Current Awardees Authors Jane Scott & Drew Carlson Analyzed 150 K08 & K99 awards Includes tips on writing a competitive K award

33. For more information

34. For more information http://projectreporter.nih.gov/reporter.cfm http://grants.nih.gov/grants/oer.hhtm www.nih.gov www.nhlbi.nih.gov

35. Office of Research Training & Career Development, Division of Cardiovascular Sciences, NHLBI, NIH: 301.435.0545 Jane Scott, ScD, MSN Drew Carlson, PhD Tawanna Meadows, BS

36. NIH Research Training Opportunities Questions???

37. NHLBI: People…Science…Health