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1. 23 Feb. 2010 Capillaries-&-Veins.ppt 1 Capillaries & Veins
2. 23 Feb. 2010 Capillaries-&-Veins.ppt 2 Capillaries Capillaries
Tiny, thin-walled vessels penetrating nearly all tissues
Enormous area for exchange between blood and tissues.
3. 23 Feb. 2010 Capillaries-&-Veins.ppt 3 Capillaries Mechanisms of exchange
Filtration
Leakage by hydrostatic pressure
Recovery of fluid at venous end
Balance of fluid recovered by lymphatic capillaries.
4. 23 Feb. 2010 Capillaries-&-Veins.ppt 4 Capillaries Mechanisms of exchange
Diffusion
O2
Glucose
Amino acids
CO2
Ammonia, NH3
Urea
Hormones
5. 23 Feb. 2010 Capillaries-&-Veins.ppt 5 Capillaries Mechanisms of exchange
Osmosis
Loss/gain of water depending on osmotic pressure
6. 23 Feb. 2010 Capillaries-&-Veins.ppt 6 Capillaries Mechanisms of exchange
Vesicular transport
Endothelial cells take large proteins from blood into vesicles,
Released outside capillary
Albumins, antibodies.
7. 23 Feb. 2010 Capillaries-&-Veins.ppt 7 Capillaries Regulation of capillary circulation
Precapillary sphincters open or close individual capillaries
Neural (ANS) control
Hormonal control
Local conditions
8. 23 Feb. 2010 Capillaries-&-Veins.ppt 8 Capillaries Long-term changes
Angiogenesis—growth of new capillaries into growing tissues
Wound healing
Tumors ?
9. 23 Feb. 2010 Capillaries-&-Veins.ppt 9 Veins Veins normally hold ~65% of blood volume
Blood reservoir
Venous flow
Little pressure to drive flow
Valves direct flow, prevent backflow
10. 23 Feb. 2010 Capillaries-&-Veins.ppt 10 Veins Venous “pumps”
Respiratory pump
Muscular pump