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Patent Ductus Arteriosus Occlusion Device Oral Presentation #1

Patent Ductus Arteriosus Occlusion Device Oral Presentation #1. Group 6 David Brogan, Darci Phillips & Daniel Schultz Advisor: Dr. Thomas Doyle. Patent Ductus Arteriosus (PDA). Ductus arteriosus (DA) allows blood to bypass pulmonary and enter systemic

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Patent Ductus Arteriosus Occlusion Device Oral Presentation #1

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  1. Patent Ductus Arteriosus Occlusion DeviceOral Presentation #1 Group 6 David Brogan, Darci Phillips & Daniel Schultz Advisor: Dr. Thomas Doyle 1/15/2003

  2. Patent Ductus Arteriosus (PDA) • Ductus arteriosus (DA) allows blood to bypass pulmonary and enter systemic • Usually DA closes within 10-18 hrs of delivery (if not deemed abnormal/patent) • PDA occurs in 1/2500-5000 live births • Many adverse effects (growth retardation, breathlessness or lack of appetite • Most common problem is congestive heart failure 1/15/2003

  3. Current Treatments • Drug therapy (indomethacin) • Implantable devices (most common are coils) • Usually need 3-4 coils • Difficult to remove and reposition • Invasive surgery (ligate the PDA to inhibit blood flow) 1/15/2003

  4. Project Goals • To design, develop and patent a PDA occlusion device that can… • Be delivered via a catheter • Conform to the shape of the PDA and cause occlusion • Can be repositioned • Be cost effective (<$200) • Provide an initial success rate of 100% 1/15/2003

  5. Our Design 1/15/2003

  6. Current Status • Conducted extensive research on other treatment methods (to avoid short comings on our design) • Design refinement finalization • PDA Device prototype • Design testing apparatus • Making adjustments to website 1/15/2003

  7. Needs • Inquired with multiple companies about … • Biocompatible and expandable foam • Biocompatible memory wire • Have not received a response and thus are seeking assistance from a biomaterials expert 1/15/2003

  8. Future Direction • Build a test device for the Patent Ductus environment • Conduct strength and pressure testing • Refine design based upon testing • Build scaled prototype with correct biomaterials • Talk with Dr. Doyle about patenting this PDA Occlusion Device 1/15/2003

  9. Contact Information • David Brogan • david.m.brogan@vanderbilt.edu • 1-210-364-4546 • Darci Phillips • darci.j.phillips@vanderbilt.edu • 1-615-386-9015 • Daniel Schultz • daniel.j.schultz@vanderbilt.edu • 1-615-421-6067 1/15/2003

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