1 / 14

Patent Ductus Arteriosus Occlusion Device

Patent Ductus Arteriosus Occlusion Device. Christina Mathieson Trung Nguyen Advisor: Dr. Tom Doyle BME 273 – Senior Design Project. Patent Ductus Arteriosus: General Information. Connection of aorta and pulmonary artery Functionally beneficial prior to birth

jameslyon
Download Presentation

Patent Ductus Arteriosus Occlusion Device

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Patent Ductus Arteriosus Occlusion Device Christina Mathieson Trung Nguyen Advisor: Dr. Tom Doyle BME 273 – Senior Design Project

  2. Patent Ductus Arteriosus:General Information • Connection of aorta and pulmonary artery • Functionally beneficial prior to birth • Maintained by low oxygen and high prostaglandins • Usually closes within 10-18 hours of birth • Abnormal if patent after 3 months • 1 in 2500 • Female:male 2:1

  3. Patent Ductus Arteriosus:Causes • All factors unknown • Prematurity of infant • Rubella infection • Random

  4. Patent Ductus Arteriosus:Effects • Increased volume load on left atrium and ventricle • Distention and dilation • Delay in postnatal pulmonary vascular changes • Growth retardation, breathlessness, poor feeding • Congestive heart failure • Bacterial endocarditis, aneurysm of ductus

  5. Patent Ductus Arteriosus:Shapes Type A: Cone Type B: Window Type C: Tube Type D: Aneurismal Type D: Irregular Cone

  6. Current Treatments: Surgery • Left posterolateral thoracotomy • Ligation or dissection • Chest tube 24hrs • Hospital 6-7 days • 6-8 month recovery

  7. Current Treatments: Coils • Most common method • Use multiple coils • Materials: • Surgical grade stainless steel • Dacron fibers • Problem: • Cannot occlude smaller PDAs • Easily dislodge when too many coils

  8. Current Treatments: Rashkind • Double Umbrella • Polyurethane fabric on stainless steel frame • Wire frame limits sizes • Must pre-order based on approx. size of PDA

  9. Our Goals • PDA occlusion device • Delivered via 6 – 7F catheter • Effective for all ages • Conforms to various shapes of PDA • Able to retract and reposition • Biocompatible material (foam) • Low cost

  10. Project Timeline Currently, have basic design idea. Goal for this month: develop testing prototype, determine material, create delivery system

  11. Work Completed • Research • PDA background: current treatments, material ideas, catheter sizes • Device shapes: Rashkind, coils, etc. • Determined Shape: Mushroom • Ideas: • Delivery system • Materials

  12. Mushroom Shape • Flat top in Aorta • Conical / Tubular base in PDA • Top prevents dislodging • Base provides surface for coagulation

  13. Delivery System • 6-7 F catheter • Similar to Rashkind implantation procedure • Enter PDA via Pulmonary Artery

  14. Future Work • Modify mushroom shape to prevent puckering • Improve delivery system idea • Finalize material selection • Build prototype • Look into methods of testing device

More Related