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The Digestive System. Structure and function. Two groups of organs. Alimentary canal (GI tract) Mouth to anus Accessory organs Mechanical breaking down food Secretions that chemically break down food. The process of digestion. Ingestion Secretion Mixing and propulsion Digestion
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The Digestive System Structure and function
Two groups of organs • Alimentary canal (GI tract) • Mouth to anus • Accessory organs • Mechanical breaking down food • Secretions that chemically break down food
The process of digestion • Ingestion • Secretion • Mixing and propulsion • Digestion • Absorption • Excretion (defecation)
Discussion will require a little knowledge of: • Control- nervous and endocrine systems • Transport- circulatory system • Smooth muscle function
Structure of the GI tract (deep to superficial) • Mucosa • Submucosa • Muscularis • Serosa
Mucosa (inner lining) • Several types of epithelium • Stratified squamous in mouth, pharynx, esophagus, anus • Simple columnar epithelium in stomach and intestines • Secretory cells • Mucus, acid, hormones
Mucosa, continued • Lamina propria • Connective tissue • Blood and lymphatic vessels • MALT (immune function) • Muscularis mucosa • Increase surface area for absorption
Submucosa • Connective tissue • Binds mucosa to muscularis • Submucosal plexus (plexus of Meissner) • Secretions and blood supply • Glands and lymphatic tissue
Muscularis- voluntary and involuntary • Skeletal muscle in upper digestive tract and anal sphincter • Smooth muscle in two layers: inner circle and outer longitudinal • Myenteric plexus (plexus of Auerbach) • Muscular contractions
Serosa- superficial membrane • Part of it forms portion of peritoneum (visceral peritoneum) • Covers organs in the peritoneal cavity • Parietal peritoneum lines walls of abdominopelvic cavity
Peritoneum is extensively folded • Folds help hold organs in place • Lots of blood supply and nerves
Peritoneal folds • Greater omentum • Adipose tissue • Immune function • Lesser omentum • Falciform ligament • Attaches liver to anterior abdominal wall and diaphragm • Mesentery • Mesocolon
The mouth- formed by cheeks, hard and soft palates and tongue
Salivary glands • Parotid • Sublingual • Submandibular • Many other minor salivary glands • Saliva lubricates, dissolves and begins to break down food • Amylase • Lipase • Lysozyme • Stimulated by parasympatheitc nervous system
Pharynx • Nasopharynx- respiration • Oropharynx • Laryngopharynx- both functions • Contractions propel food into esophagus
Esophagus- posterior to trachea • Transports food without digestive activity • Peristalsis • Upper and lower esophageal sphincters • Delivers food to stomach
GERD (gastroesophageal reflux disease) • Controlled diet • Histamine-2 blockers (Tagamet, Pepcid AC). Good for hearthburn but not inflammation • Antacids- (bicarbonate) • Proton pump inhibitors (Prilosec, Prevacid, Nexium • pro-motility drugs increase action of muscles of digestive system (Reglan) • Foam barriers