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Prof David Baud, MD PhD Switzerland. Uterine artery embolization for PPH. Maternal death. Prevention. Be aware of risk factors Treat anaemia antenatally Active management of the 3 rd stage Prophylactic oxytocics = reduce risk of PPH by 60% ( oxytocin or ergometrine ) Causes: 4T
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Prof David Baud, MD PhD Switzerland Uterineartery embolization for PPH
Prevention • Be aware of risk factors • Treat anaemia antenatally • Active management of the 3rd stage • Prophylactic oxytocics = reduce risk of PPH by 60% (oxytocin or ergometrine) • Causes: 4T • Tone 70% • Trauma 20% • Tissue 10% • Thrombin 1%
Medical Surgical / invasive
B-Lynch /Ut. Art. ligation Uterine arteryembolisation Gelatinsponge, Gelfoam, alcoholparticles, microparticles
Vascular injuries 1-2%
Other complications • Vascular injuries • Endometritis • Distant necrosis • Limb • Intestine • Buttock • Fistula • Ovaries => failure? • Uterinenecrosis
Menstrual cycle • Return to normal in 81% of patients
Pregnancies after UAE • 38 studies with long F/U = 1072 patients • 23% had subsequent pregnancies • Among 499 patients who were asked whether they were attempting pregnancy, 35% answer YES- 76% were able to conceive - delay to conceive = 4-12 months - uterine synechiae as cause of infertility - Normal birth weight - more placenta accreta (20%) - 20% recurence PPH
Method • Retrospective study • All patients treated with embolization for PPH • 2003 – 2013 • Outcomes: • Gynaecological symptoms • Future fertility • Obstetrical outcomes • Psychological impact
Matching 1:3 Maternal age Ethnicity Year of delivery Parity Mode of delivery Birth weight Gestational age
Conclusion After embolization for PPH: SIMILAR menstrual cycle SIMILARsexual function SIMILARfertility, but... Subsequent pregnancies: Time to achieve a new pregnancy is longer after UAE Fear to get pregnant might be a major factor SIMILARobstetrical complications, except for recurrence of PPH and cesaerian
Post-traumatic stress disorder Walters JT, Bisson JI, Shepherd JP. Predicting post-traumatic stress disorder: validation of the Trauma Screening Questionnaire in victims of assault. Psychol Med. 2007 Jan;37(1):143-50. Epub 2006 Sep 7
Conclusions • Preserved fertility after embolization • Good pregnancy outcomes after embolization, except recurrent PPH & CS!! • Do not underestimate Post-Traumatic Stress !!! • Also partner
THANKS Francoise Damnon KarineLepigeon Dominique Bertaud MathildeMorisod Maude Bernasconi