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Exploring the Lymphatic System: Vessels, Organs, and Tissues

Delve into the intricate network of the lymphatic system, understanding its vessels, organs, and tissues, from lymph nodes to the spleen and thymus. Learn about fluid dynamics, lymph node structure, and diagnostic procedures for lymphatic issues.

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Exploring the Lymphatic System: Vessels, Organs, and Tissues

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  1. Lymphatic System Vessels, Organs and Tissues

  2. Lymphatic System • Vessels: Connect to CV • Lymphatics • Capillaries • Collecting vessels • Trunks • Transport fluid => lymph • Organs: house immune cells • LN • Spleen • Thymus • Tissues • Tonsils • GALT • MALT

  3. Fluid Compartments • Capillary Dynamics • Hydrostatic/Hydraulic • Osmotic • Fluid Compartments • ICF • ECF • ISCF • Plasma • Lymph

  4. Lymphatic Capillary

  5. Lymph Flow

  6. Lymphatic Valve

  7. Lymphatic Vessels and Ducts

  8. Thoracic Duct

  9. Lymph Return

  10. Problem Lymph Return : Lymphedema

  11. Lymphatic Vessel Circuits

  12. Lymph Node: Location

  13. L.N. : Specimen

  14. Lymph Node: Gross Anatomy • 1. Afferent Lymphatics • 2. Cortex • 3. Germinal Center • 4. Capsule • 5. Medullary cord • 6. Valve • 7. Efferent Lymphatics

  15. LN Structure: CT and vessels • Capsule • Subcapsular sinus • Trabecula • Reticular CT stroma • Vessels • Types • Afferent • Efferent • Valves

  16. Lymph Node

  17. Lymph Node: Histology B cells T cells MO

  18. Lymph Node: Capsule Region

  19. Lymph Node: Cortex Lymphatic Nodule Germinal Center

  20. Lymph Node: Medulla

  21. Lymph Node: Medullary Cords Medullary Cords Sinusoids Macrophages

  22. L.N. Medullary Cells • P = Plasma cells (daughter cells of Activated B cells • M = Macrophages (mature monocytes in tissues)

  23. LN Histology Summary

  24. Diagnostics for Lymphatics and LN Lymphangiogram

  25. Lymphatic Problem: Lymphoma

  26. Lymphatic Nodule: Basic structure for All Lymphatic tissue

  27. Spleen: Location

  28. Spleen: Gross Anatomy

  29. Spleen: Histology Splenic Sinusoid

  30. Spleen Problems • Rupture • Cancer • Infection Hydatid cyst

  31. Thymus: Location

  32. Thymus: Gross

  33. Thymus Embryological Development • 1. Mandibular arch • 2. Hyoid arch • 3. Cervical sinus entry • 4. 3rd pharyngeal pouch • 5. 4th pharyngeal pouch • 6. Foramen cecum • 7. Thyroid • 8. Cervical sinus • 9. Thymus (3rd pouch) • 10. Thymus (4th pouch)

  34. Thymic Cell Development • 1. Thymic capsule • 2. Thymic nurse cells • 3. CT septa and BV • 4. Subcapsular epithelium (for the blood thymus barrier) • 5. Cortical Epithelial cells • 6. Medullary epithelial cells • 7. Dendritic cells • 8. Hassall’s Corpuscle • 9. Macrophages • 10. Cortex • 11. Medulla

  35. Thymic Organization

  36. Thymic Capsule, Septa and Lobules

  37. Thymus: Cortex

  38. Thymic Medulla

  39. Thymic Age Degeneration

  40. Thymic Problem Thymic Aplasia

  41. Tonsil: Location • Pharyngeal [Adenoids] • Palantine • Lingual • Tubal

  42. Palatine Tonsil

  43. Tonsil: Epithelial Histology

  44. Tonsil Lymphatic Nodules

  45. Tonsilar Crypt

  46. Tonsil Problem: Tonsillitis

  47. Gut Associated Lymphatic Tissue (GALT) Location

  48. GALT

  49. Peyer’s Patches

  50. Ileum Problems Inflammation Necrosis

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