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Water, electrolyte, and acid-base balance. Distribution of body fluid. Most fluid is inside the cells Interstitial- spaces Blood plasma Lymph “ transcellular ” fluid What is fluid? Water and solutes Fluid moves between compartments. What is in the body fluid?.
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Distribution of body fluid • Most fluid is inside the cells • Interstitial- spaces • Blood plasma • Lymph • “transcellular” fluid • What is fluid? • Water and solutes • Fluid moves between compartments
How does fluid move around? • Hydrostatic pressure pushes fluid from plasma outward • Colloid osmotic pressure brings it back to the plasma
Electrolyte balance • What are they • Intake (dietary) • Output: • Normal body excretion • Hormones • Aldosterone • Parathyroid hormone • Active transport in kidneys
Buffers help prevent acid-base imbalance • Chemical buffer systems are present in blood • Physiological systems act more slowly
What are the symptoms of acid-base imbalance? • Acidosis • CNS shuts down • Breathing, circulation affected • Alkalosis • Dizziness • Agitation • Tingling sensations • Imbalances in other electrolytes can also cause disease • Sodium imbalance affects CNS; potassium, muscles
Summary • Water and electrolyte balances are critical for homeostasis • Kidneys are especially important for “correcting” imbalances (the site of activity of many hormones) • Physical, chemical and endocrine mechanisms are all required
Review question 1 • In the body, most of the water is located in the : • A. blood • B. lymphatic vessels • C. cells • D. in the spaces between the cells • E. It is evenly distributed throughout the body
Review question 2 • On average, most water is lost from the body through: • A. Sweating • B. Urine • C. As a component of feces • D. Breathing water vapor • E. Tears
Review question 3 • Which of these digestive organs does not absorb water? • A. Stomach • B. Small intestine • C. Large intestine • D. Esophagus • E. They all absorb water
Review question 4 • Which of these is not an electrolyte? • A. Sodium • B. Glucose • C. Chloride • D. Bicarbonate • E. Potassium