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Some of the ongoing projects in the aphasia research laboratory

Some of the ongoing projects in the aphasia research laboratory. Our central focus is to examine the nature of language recovery in the brain. Recovery in a damaged brain?. Normal Brain. Our rehabilitation for patients with aphasia involves several weeks of language therapy.

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Some of the ongoing projects in the aphasia research laboratory

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  1. Some of the ongoing projects in the aphasia research laboratory

  2. Our central focus is to examine the nature of language recovery in the brain Recovery in a damaged brain? Normal Brain

  3. Our rehabilitation for patients with aphasia involves several weeks of language therapy

  4. Several of our rehabilitation projects examine the notion of semantic complexity X Clothing X Kiran (2008), Journal of Speech Language and Hearing Research

  5. Oral Naming Written Naming Oral Reading Written spelling

  6. Rehabilitation of language deficits

  7. Our bilingual aphasia therapy examines Between and within language generalization Kiran et al., AJSLP, 2013

  8. We examine Neuroimaging of language recovery in the brain P1 PAPT P1 PN NC1 PAPT NC1 PN

  9. Network changes after rehabilitation • Specific patterns of activation may inform regions that may change- but not necessarily how they are modulated within a network. • Understanding changes in activation and changes in network connectivity will provide a better understanding of the dynamics of language recovery.

  10. Our studies of functional connectivity tell us important hubs in the recovered brain LSFG • Across all patients, LIFG is the most modulated region after treatment • RIFG-RMFG most modulated connection • More modulation in the LH LMFG RMFG LIFG RIFG LPCG RSTG LAG RAG 3 2 5 1 4 6 3 2 LFUS RFUS 1 LITG RITG Kiran et al., in prep

  11. Node Degree Patient Count NodeStrength Patient Count Trained Abstract Network 1.9 ---- 4.3 1.3 ---- 7.0 2 ------- 7 2 ------- 9 Node Degree Node Strength Direct training = increased connectivity for abstract regions

  12. Neuroimaging of language in bilingual aphasia • Activation maps for participants with aphasia. ‘Red’ represents English > control, ‘Blue’ represents Spanish> control and ‘Purple’ represents overlap in activation. Statistical maps are thresholded by using clusters determined by Z > 2.3 and a (corrected) cluster significance threshold of P = 0.05. Images are in radiological orientation with the right side the brain to the left and the left side to the rights.

  13. Computational simulation of bilingual aphasia rehabilitation • (Kiran et al., 2012; BLC)

  14. Category learning in aphasia

  15. Validation of ipad therapy for patients for aphasia In collaboration with Constant Therapy, INC

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