Anti-cancer activity of Carica papaya leaf ethanolic extract and fractions

The anti-cancer activity of Carica papaya leaf ethanolic extract and ethyl acetate fraction were evaluated against selected human cancer cell lines by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The leaf ethanolic extract of C. papaya was subjected to fractionation by using hexane, chloroform and ethyl acetate to separate compounds based on their polarity. The ethanol and ethyl acetate fraction of the plant were tested for their cytotoxic and anti-cancer activity against HCT- 116 human colon cancer cell line; mcF7 u2013 human breast cancer cell line.

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Anti-cancer activity of Carica papaya leaf ethanolic extract and fractions

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