1 / 7

$1k Genome

$1k Genome. Presentation by Kyle Bolton. Why?. Would be nice to understand “human genomic diversity, encompassing all types of variation beyond common single-nucleotide variants.” (1) “mapping full genomes, scientists argue, is the key to individualized genetic information” (2) .

iram
Download Presentation

$1k Genome

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. $1k Genome Presentation by Kyle Bolton

  2. Why? • Would be nice to understand “human genomic diversity, encompassing all types of variation beyond common single-nucleotide variants.”(1) • “mapping full genomes, scientists argue, is the key to individualized genetic information”(2)

  3. As of march 2010(2) • Knome $99,000 for whole genome • Illumina,Inc. announced sequencer that takes 1 week and $10,000per genome • HelicoseBioSciences mapped scientist Stephen Quake’s genome for $50,000. • Other players include • Applied Biosystems • 454 Life Sciences (a Roche company) • Complete Genomics • Pacific Biosciences • Ion Torrent Systems • Has a pH chip that can sequence “hundreds of millions of base pairs for $500”

  4. As of August 2010(3) • “ABI's SOLiD 4 platform has been said to generate a $6,000 genome, and the SOLiD 4 hq upgrade is planned for this fall with a target of delivering a $3,000 genome, Robison says” • Illumina’s ”HiSeq is supposedly at a $10,000 genome already” • “IonTorrent may only be two years away” • Complete Genomics • Life Technologies

  5. Factors for winner • Not necessarily the first product who’s materials cost is <=$1k • Accuracy • Equipment Cost • Maintenance • Training Required (foolproofing, even) • If inflation increases fast enough, and the cost lowers slow enough, it may prevent the cost from ever reaching $1k.

  6. Potential for (ab)use • Insurance companies • Employers • Criminal Justice Systems • Info Brokers • Medical Professionals • Drug Companies

  7. Sources • 1 “Anticipating the $1,000 genome” by Elaine R Mardis. doi: 10.1186/gb-2006-7-7-112. • 2 “Pacific BioScience Has A $1000 Genome Test That Could Save Your Life -- and the Industry” By Rachel Lehmann-Haupt. Pulbished on http://www.bnet.com/blog/healthcare/, March 4, 2010. • 3 “The 'Arbimagical' Goal of the $1,000 Genome” editorial? Published on http://www.genomeweb.com/blog, August 30, 2010

More Related