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Uterine sarcomas in RIPAS Hospital, Brunei; a 10 year retrospective study. Dr Alice Kurien, Dr Saw Ohnmar, Dr Hjh Roselina Yaakub. Department of Obstetrics & Gynaecology, RIPAS Hospital, Brunei Darussalam. LOGO. OPTIONAL HERE. Conclusions. Objectives. Results.
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Uterine sarcomas in RIPAS Hospital, Brunei; a 10 year retrospective study. Dr Alice Kurien, Dr Saw Ohnmar, Dr Hjh Roselina Yaakub.Department of Obstetrics & Gynaecology, RIPAS Hospital, Brunei Darussalam LOGO OPTIONALHERE Conclusions Objectives Results Total cases of uterine corpus cancer -156 Uterine Sarcoma - 37(23.7% ). • Higher proportion of uterine sarcoma among women with corpus cancer in Brunei . • Mean Age was 47.8 years • One or more risk factors in • 78 % patients. • Multiple risk factors noted in 30% • 63% are disease free after 5 • years follow up. • 70% are alive & well. • Disease stage was the most important prognostic factor. • Further research is required to identify the cause of higher incidence in the study population. • To evaluate : • Demographic profile • Risk factors • Diagnostic issues • Clinical outcome Yearly distribution Parity distribution Age distribution Methods All patients with uterine sarcoma registered in the department of Obstetrics and Gynaecology in RIPAS hospital from 2001 to 2010 were studied. Cases were identified through the gynaecology oncology registry of the department. This was a retrospective case file analysis. The data was recorded in a pre-designed proforma and a detailed analysis was done. Prior approval from Brunei Darussalam Medical & Health Research Ethics Committee was obtained. References FIGO stage 1. Vanessa N Harry et al. Review uterine sarcomas: The Obstetrician & Gynaecologist.2007; 9: 88-94. 2 Jonathan S Berek, Neville F Hacker: Practical Gynecologic Oncology 4th edition.2005; 430-435. 3. Michael Quinn et al: Malignant disease of the uterus. Shaw’s text book of gynecology th edition 644-8. 4.McCluggage WG Uterine carcinosarcomas (malignant mixed mullerian tumors) are metaplastic carcinomas. Int J Gynecol Cancer.2002 Nov-Dec;12(6):687-90 5 .KernochanLE,Garcia RL. Carcinosarcomas (malignant mixed mullerian tumor) of the uterus: advances in elucidation of biologic and clinical characteristics. 6. Zelmanowicz et al .Evidence for a common etiology for endometrial carcinoma and MMMT. Gynaecol Oncol 1998;69:253-257 7. Norris HJ , Taylor HB. Post irradiation sarcomas of the uterus. Obstet Gynaecol1965; 26:689-693. 8 Philip J. DiSaia, William T.Creasman. Clinical Gynecologic oncology.169-74. Survival status