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Nanoscale Communication : Energy and Information. Tap the existing world of biological nanotechnology by constructing molecular level, functional interfaces between living systems and synthetic technology Domesticate life at the molecular and cellular level
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Nanoscale Communication:Energy and Information Tap the existing world of biological nanotechnology by constructing molecular level, functional interfaces between living systems and synthetic technology Domesticate life at the molecular and cellular level Develop design and fabrication principles that enable the construction of synthetic devices, with capabilities that rival those of living systems Bottom-up design and construction
Two Nanoscale Revolutions Technology Biology • Technology, by human design • Nanoscale dimensions beginning to be achieved • Nanoscale properties harnessed in isolated examples • Very limited capabilities compared with living systems • Self-evolving • Scientific understanding by discovery • Intrinsically nanoscale • Innumerable unique properties • Capabilities generally can not be harnessed
Existence is Established All aspects of life are naturally emergent physical properties • What is it about living systems that enables them to perform such tasks? • What is the technology? • Can similar levels of functionality be engineered into synthetic systems? • Can these functionalities be harnessed? • Can living and nonliving be integrated?
Nanoscale Communication:Energy and Information 5.1 Interfacing biological and nonbiological 5.2 Nano-macro junctions 5.3 Energy transduction at the nanoscale 5.4 Functional nanoscale systems and colonies
5.1 Integrating living and nonliving • Actively communicate with and direct cellular behavior • Real-time two-way communication as in living organism • Decode biological communication principles • Establish synthetic (molecular-level) communication with living cells • Develop minimal self-sustaining (living or nonliving) organism • Bottom-up synthetic cell • Top-down minimal cell
Breaking the Living-Nonliving Barrier Living receptor protein Synthetic receptor protein Living cell Carbon nanotube Synthetic cell membrane Solidstate electronics
5.2 Nano-macro junctions • Photonic • Plasmonics and subwavelength light control • Electrical/Magnetic • Molecular wirebonds • Mechanical • Chemomechanical motor drive • Combining different approaches
Photon/Electron transduction Electron/Photon transduction at quantum limit Nanowire optoelectronics Nanotube LED with tunable junction location
5.3 Energy Transduction at the Nanoscale • Photonic, electronic, and chemical transitions • Photon – electron/ion coupling • Photon - chemical coupling • Etc. • Stochastic processes, signals and noise • Biological signal transduction and information processing • Molecular motors
5.4 Functional nanoscale systems and colonies • Building nanoscale assemblies • Self-regulating adaptive interactive systems • Metabolism • Information replication • Self-replicating life • Ad-hoc networking among nanoscale devices
Quorum sensing: nano to mega Self-organiation on the megameter scale PNAS October 4, 2005 vol. 102 no. 40 14181–14184
Conceptual Origins Maxwell: control randomness Mendel: use randomness
Conceptual Origins Maxwell: control randomness Mendel: use randomness Random biological evolution has developed technology that controls randomness