1 / 6

V max and Km of Enzyme-controlled Reactions

V max and Km of Enzyme-controlled Reactions. V max. The maximum rate at infinite substrate concentration is called V max. K m. The substrate concentration that give a rate of 1/2 V max is called K m.

jaegar
Download Presentation

V max and Km of Enzyme-controlled Reactions

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Vmax and Km of Enzyme-controlled Reactions

  2. V max • The maximum rate at infinite substrate concentration is called Vmax.

  3. K m • The substrate concentration that give a rate of 1/2 Vmax is called Km.

  4. These quantities are useful for characterizing an enzyme. A good enzyme has a high Vmax and a low Km.

  5. Vmax and Km for Competitive Inhibition • Competitive inhibitors increase Km for the enzyme, but have no effect on Vmax, so the rate can approach a normal rate if the substrate concentration is increased high enough.

  6. Vmax and Km for Non-competitive Inhibition • Non-competitive inhibitors therefore simply reduce the amount of active enzyme (just like decreasing the enzyme concentration), so they decrease vmax, but have no effect on KM.

More Related