1 / 10

Nitric Oxide (Nitrogen monoxide) Endothelial Relaxing Factor (EDRF).

Nitric Oxide (Nitrogen monoxide) Endothelial Relaxing Factor (EDRF). *組員 B9902080 廖佩炫 B9902095 盧翰生. How nitric oxide is produced?. L-arginine + 3/2 NADPH + H + + 2 O 2 citrulline + nitric oxide + 3/2 NADP +. How nitric oxide is produced?. 1.Unrelated to body.

jamalia-langley
Download Presentation

Nitric Oxide (Nitrogen monoxide) Endothelial Relaxing Factor (EDRF).

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Nitric Oxide (Nitrogen monoxide)Endothelial Relaxing Factor (EDRF). *組員 B9902080 廖佩炫 B9902095 盧翰生

  2. How nitric oxide is produced? L-arginine + 3/2 NADPH + H+ + 2 O2 citrulline + nitric oxide + 3/2 NADP+

  3. How nitric oxide is produced? 1.Unrelated to body • Reduction of inorganic nitrate • By Nitroglycerin and amyl nitrite • Nitric oxide is generated by phagocytes • Nitric oxide is released by neurons 2.related to body

  4. Effects of nitric oxide to the human body;Vasodilation.(Penile Erection) Mechanisms of NO Action NO is formed diffuses into the blood diffuses into the muscle cells activates guanylyl cyclase dephosphorylation of GTP signalling smooth muscle relaxation

  5. Effects of nitric oxide to the human body;Neurotransmission Modifying electrical activity of neurons

  6. Carbon monoxide Carbonous oxide

  7. How is carbon monoxide produced • Generated by the enzyme heme oxygenase (HO) (where it is found in the neurons in the brain or PNS ) - first example • Vertebrate body produces small amount of CO • During heme metabolism

  8. Production of the Carbon Monoxide

  9. Effects of Carbon monoxideVasodilation Carbon Monoxide produced activation of calcium-activated potassium channels inducing hyperpolarizing outward currents called STOCs smooth muscle hyper-polarization Vasodilation

  10. 參考資料 http://www.google.com.tw/images?um=1&hl=zh-TW&biw=1076&bih=412&tbs=isch%3A1&sa=1&q=MUSCLE+CELL&aq=f&aqi=g1&aql=&oq= http://en.wikipedia.org/wiki/Carbon_monoxide http://en.wikipedia.org/wiki/Heme http://nitricoxidewarning.com/nitric-oxide-supplements-find-the-best-nitric-oxide-supplement/ http://www.bewellbuzz.com/general/amazing-benefits-nitric-oxide/ http://blog.udn.com/jnwu/3958716 http://www.forcefactorsuccess.com/best-nitric-oxide-supplements http://www.phagocytes.net/groups/erwig.html http://www.boatingsidekicks.com/cobro/cobrochure.htm http://www.cdc.gov/co/faqs.htm http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/learning-center/plasma-blood-protein/hemoglobin-heme-products.html http://psychology.kenyon.edu/psy_111/week5.htm http://jap.physiology.org/content/100/3/1065.full http://jap.physiology.org/content/100/3/1065/F1.expansion.html http://ajrccm.atsjournals.org/cgi/content/full/171/4/354 http://en.wikipedia.org/wiki/Myosin_light_chain_phosphatase

More Related