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BIOMEDICAL ENGINEERING. BIOMEDICAL ENGINEERING. New Graduate Student Orientation Fall 2005 Welcome Aboard!. BIOMEDICAL ENGINEERING. Orientation Schedule. 9:15 Continental Breakfast- BME Conference room 9:45 Donna Beck - Engineering and Science Library
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BIOMEDICAL ENGINEERING BIOMEDICAL ENGINEERING New Graduate Student OrientationFall 2005Welcome Aboard!
BIOMEDICAL ENGINEERING Orientation Schedule 9:15 Continental Breakfast- BME Conference room 9:45 Donna Beck - Engineering and Science Library 10:30 Michele DiPietro - Eberly Center for Teaching Excellence 11:00 BME Staff Hilda Diamond – Associate Head Sandy Brenner Hill – Business Manager Christal Banks – Office Coordinator 11:30 Jeff Beyer - Counseling &Psychological Services 12:15 Todd Przybycien - BME Department Head 12:45 Lunch
BIOMEDICAL ENGINEERING BME Office • Ms. Christal Banks, Office Coordinator (cbanks@andrew.cmu.edu) • Mailboxes, appointments, events • Mrs. Hilda Diamond, Associate Head (hd01@andrew.cmu.edu) • Degree progress and records issues • Course registration issues • Ms. Sandy Brenner-Hill, Business Manager (sb5v@andrew.cmu.edu) • Stipend and tuition issues • BME purchasing issues • Prof. Todd Przybycien, Head (todd@andrew.cmu.edu) • Advisor assignments • Programmatic issues • Problem solving • Prof. Jelena Kovacevic, Graduate Affairs Chair (jelenak@andrew.cmu.edu) • Coordination of qualifying exams • Coordination of grad student reviews • Degree requirements and petitions • Problem solving
BIOMEDICAL ENGINEERING Student Introductions/Assignments • Ph.D. students • Jonathan Didier, CMU, BS ChE – open TE/biotech • Paul Glass, McGill Univ., BS ME – DiMartino/Sitti • Charles Jackson, Univ. Canterbury, BS EE - Kovacevic • Rowena Mittal, MIT, BS ChE - Washburn • Warren Ruder, MIT, BS ChE, ME - Antaki • Gail Siewiorek, Washington Univ, BS BME – open biomech • Steve Sun, Univ. Washington, BS Biochem - Washburn
BIOMEDICAL ENGINEERING Department Overview Biomedical Image & Signal Informatics Computational Biomechanics & Devices Medical Robotics Molecular & Cellular Biotechnology Regenerative Medicine Biomedical Image & Signal Informatics
BIOMEDICAL ENGINEERING Molecular & Cellular Biotechnology Carnegie Mellon • Bruce Armitage (Chem) – DNA-small molecule interactions, peptide nucleic acids • Mike Domach (ChE) –metabolic engineering, whole cell NMR, cell-tracking MEMS sensors • Steinar Hauan (ChE) – bioprocess and biosensor design and optimization • Todd Przybycien (BME & ChE) –protein separations, formulation, delivery; DNA formulation • Jim Schneider (ChE) –nucleic acid separation, formulation and delivery; interfacial interactions • Bob Tilton (BME & ChE) –protein adsorption; pharmaceutical dispersions; interfacial interactions
BIOMEDICAL ENGINEERING Molecular & Cellular Biotechnology Carnegie Mellon • Jeanne VanBriesen (CEE)–biofilm control on inplants • Alan Waggoner (BSC) – fluorescence-based detection systems for biology and biotechnology
BIOMEDICAL ENGINEERING Computational Biomechanics & Devices Carnegie Mellon • Cristina Amon (ME & ICES) –computational fluid dynamics for enhancing mass transfer and hemodynamic performance of intravenous membrane oxygenators • Jim Antaki (BME) –artificial heart/ventricular assist device design and control, blood flow modeling • Elena DiMartino (ICES) –computational fluid and solid mechanics, soft tissue mechanical characterization • Ender Finol (ICES) –computational fluid mechanics, endo vascular grafts for abdominal aortic aneurysms • Phil Leduc (ME) -linking mechanics to biochemistry through molecular and cellular biomechanics using nanotechnology-
BIOMEDICAL ENGINEERING Biomedical Image & Signal Informatics Carnegie Mellon • Chien Ho (BSC) – tracking migration of immune cells in vivo by magnetic MRI • Jelena Kovacevic (BME) – wavelet-based signal and image processing • José Moura (ECE) – wavelet-based MRI signal processing • Bob Murphy (BME & BSC) – tracking receptor-mediated endocytosis; microscopic imaging and image analysis for protein localization • Rich Stern (ECE) – automatic speech recognition; signal processing in the auditory system • George Stetten (RI) – ultrasonic imaging
BIOMEDICAL ENGINEERING Medical Robotics Carnegie Mellon • Jon Cagan (ME) –user-centered design; computational design • Takeo Kanade (RI) –smart tools to perform medical procedures, computer vision • Yoky Matsuoka (ME & RI) –neuromuscular rehabilitation and assistive robotic devices, motor control mechanisms in the CNS, artificial neural feedback • Kenji Shimada (ME) –computer modeling and simulation for product design, analysis, and manufacturing • Lee Weiss (RI) –computer-aided bone distraction
BIOMEDICAL ENGINEERING Regenerative Medicine Carnegie Mellon • Jeffrey Hollinger (BME & BSC) –regenerating bone in patients with developmental craniofacial bone problems and geriatric patients • Prashant Kumta (BME & MSE) –biodegradable polymer-ceramic composite scaffolds for bone tissue engineering, nanoparticles for gene delivery • Phil Campbell (ICES) –growth factor association and dissociation with interstitia and proteolytic processing under physiological conditions • Newell Washburn (BME & Chem) – polymeric scaffold development • Lee Weiss (RI) – bone tissue engineering CAD/CAM
BIOMEDICAL ENGINEERING New Faculty Arrivals Carnegie Mellon • Aug 2006Biomechanics:Kris Dahl (BME & ChE) – nuclear (cell) physics • Jan 2006Imaging/Cellular & Molecular Biotechnology:Stefan Zappe (BME) –bioMEMS, automated imaging, Drosophila systematics
BIOMEDICAL ENGINEERING M.S. Requirements • 96 units (3 units ~ 1 credit hour) • 63 units grad coursework • Courses numbered xx-Nxx where N 5 • Must include 4 BME courses 42-Nxx • 24 units grad research • 42-888 MS Thesis Research • 42-886 Comprehensive Exam for MS Degree • Must have 36 units/semester to be full-time
BIOMEDICAL ENGINEERING M.S. Typical Timeline Carnegie Mellon
BIOMEDICAL ENGINEERING M.S. Defense • Basis • An original contribution (~ one archival paper) • knowledge in thesis area • approach and evaluation of results • Thesissummary of problem studied, logic of approach, results obtained, future opportunities • Oral defense • thesis committee • advisor • at least two CMU BME faculty • at least one CMU non-BME faculty • 30 min oral presentation • open Q&A
BIOMEDICAL ENGINEERING Ph.D. Requirements • Direct Entry Ph.D. • Must satisfy Masters course requirements • Need not produce M.S. Thesis • Complete “Advanced Entry” Requirements • Advanced Entry Ph.D. • Must complete 96 units 32 credit hours of courses + research • No specific course requirements; advisor and student select courses to support research effort • Successfully complete three exams: • Ph.D. Qualifying Exam • Ph.D. Proposal Exam • Ph.D. Thesis Defense • Must have 36 units/semester to be full-time
BIOMEDICAL ENGINEERING Ph.D. Requirements • All Ph.D. students complete three, 5-hr TA assignments • Gain exposure to the “other side of the desk” • Spread TA load
BIOMEDICAL ENGINEERING Course Registration • Initial Scheduling – Mrs. Hilda Diamond • Key Courses • 42-801 Seminar (every semester) • 42-702 Advanced Physiology (if no prior coursework in physiology) • 06-608 Safety Issues in Science and Engineering Practice (for those whose research will involved lab work) • Complete schedule in consultation with advisor • On-line registration (OLR) via the HUB:http://www.cmu.edu/hub/hub.html
BIOMEDICAL ENGINEERING Current BME Grad Courses • Fall • 42-501 Special Topics: Bone Tissue Regeneration – Hollinger • 42-702 Advanced Physiology – Campbell • 42-703 Advanced Bioimaging - Kovacevic • 42-711 Advanced Ceramic and Metallic Biomaterials - Kumta • 42-721 Biotechnology and Environmental Processes – Domach • Spring • 42-502 Special Topics: Cellular Biomechanics – LeDuc • 42-503 Advanced Signal and Biosignal Processing – Kovacevic • 42-710 Advanced Polymeric Biomaterials – Washburn • 42-722 BioProcess Design – Przybycien • 42-723 Biological Processes in Environmental Systems – VanBriesen • 42-734 Computational Biology - Murphy
BIOMEDICAL ENGINEERING Ph.D. Typical Timeline Carnegie Mellon
BIOMEDICAL ENGINEERING M.D./Ph.D. Typical Timeline Carnegie Mellon
BIOMEDICAL ENGINEERING Ph.D. Qualifier – Current Configuration • Basis • research potential • communication skills • general BME knowledge • knowledge of literature • approach and evaluation of results • Written statement of researchTen page (max) summary of oral presentation content • Oral presentation of research • “focused” committee of 3 faculty members • advisor participates as silent observer • 30 min presentation • 45-60 min Q&A
BIOMEDICAL ENGINEERING Ph.D. Qualifier – Current Configuration • Outcomes • Pass + comments • Retake + comments • Fail + comments; retake possible, but not recommended • Not a winnowing tool
BIOMEDICAL ENGINEERING Ph.D. Grad Student Review • Objective: assess progress in program • Basis: • Research activities & progress • Course performance • TA performance • Format • Student prepares ~one page self-assessment • Student and advisor discuss self-assessment • Advisor prepares ~one-two paragraph feedback statement • Advisor reviews feedback in front of BME faculty, incorporates comments • Statements posted on grad review web site
BIOMEDICAL ENGINEERING Ph.D. Grad Student Review – Cont’d • Outcomes: • Student in good standing + comments • Student deficient in x + comments, one review period to address deficiency • Posted on review web site along with degree progress information • Frequency – once a semester
BIOMEDICAL ENGINEERING Ph.D. Proposal • Basis • potential for making important, original contributions • feasibility of proposed work • knowledge in thesis area • approach and evaluation of results • Written proposal • definition of thesis problem, specific aims, results to date and plan of attack • ~25 pages in NIH R01 “research description” format • Oral proposal • thesis committee • advisor(s) • at least two CMU BME faculty • at least one CMU non-BME faculty • 45 - 50 min presentation • open Q&A
BIOMEDICAL ENGINEERING Ph.D. Defense • Basis • original contributions (~ 3 [or more] meaty archival papers) • knowledge in thesis area • approach and evaluation of results • Thesissummary of problem studied, logic of approach, results obtained, future opportunities • Oral defense • thesis committee – typically same as Prop Exam • advisor(s) • at least two CMU BME faculty • at least one CMU non-BME faculty • 45 - 50 min oral presentation • open Q&A
BIOMEDICAL ENGINEERING Important Resources www.cmu.edu/bme www.cmu.edu/myandrew • BME main office phone 412-268-2521 bme-faculty@lists.andrew.cmu.edu bme-grad@lists.cmu.edu – all of you sb5v@andrew.cmu.edu X83444 - Sandy hd01@andrew.cmu.edu X82523 - Hilda cbanks@andrew.cmu.edu X83955 – Christal todd@andrew.cmu.edu X83857 – Todd