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Accessing Information About Chemicals and Chemical Hazards

Accessing Information About Chemicals and Chemical Hazards. Chemical Incidents Create Various Information Needs. California: 2012 Chevron Refinery Fire. Source: abcnews.com. Texas: 2013 Fertilizer Plant Explosion. Source: U.S. Chemical Safety Board.

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Accessing Information About Chemicals and Chemical Hazards

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  1. Accessing Information About Chemicals and Chemical Hazards

  2. Chemical Incidents CreateVarious Information Needs

  3. California: 2012 Chevron Refinery Fire Source: abcnews.com

  4. Texas: 2013 Fertilizer Plant Explosion Source: U.S. Chemical Safety Board

  5. West Virginia: 2014 West Virginia Chemical Leak/Water Ban Source: wvpublic.org

  6. Chemical Information Needed • What is this chemical? • Properties (color, odor, form, weight, solubility) • Use (fuel blending, coal washing, fertilizer production, hydrodealkylation) • Is this chemical toxic/health effects? • Humans • Animals • Plants

  7. Chemical Information Needed (2) • What should be done for protection? • First responders, containment, clean up • Residents • Air, water, soil • If exposed, what should be done? • Fresh air, rinse eyes • Discontinue use of drinking water • Triage, emergency room/hospital, social worker • Potassium supplement, gastric lavage

  8. Chemical Information Needed (3) • What toxicology studies have been completed? • Journal publications • Government dbases • Industry studies • What regulations and guidelines exist from government? • Have similar incidents occurred?

  9. For Answers Search:toxnet.nlm.nih.gov

  10. Poll

  11. Searching HSDB forChemical Information Search Options: • Chemical identifiers • Name or synonym • Registry number • Query terms • Disease or health effect • Treatment method • Use

  12. Searching HSDB forChemical Information (2) Limits Feature • Displays major sections • Expands to display many data fields • Targeted search • Multiple chemicals in results

  13. Open browser to demonstrate searching HSDB

  14. Question/Poll Do these names represent the same chemical? • 4-Methyl-1-cyclohexanemethanol • 4-Methylcyclohexanemethanol • MCHM • 4-MCHM • p-Methylcyclohexanemethanol

  15. Answer: Yes Types of names include: Systematic (IUPAC-International Union of Pure & Applied Chemistry) Common Trade Street

  16. West Virginia Chemical Spill MCHM: Challenges creating a new HSDB record • 4-Methylcyclohexanemethanol • HSDB sources • Limited data available • Peer review of record • Releasing record to the public

  17. Open browser to show MCHM record in HSDB

  18. Questions ? Presenter: Shannon M. Jordan, MPH National Library of Medicine shannon.jordan1@nih.gov

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