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parsley is not amenable to forward genetics. NHL25. NHL3. Innate immunity – A common theme in mammals, Drosophila and plants (1). Pathogen-associated molecular patterns (PAMP) are recognized by pattern. recognition receptors and trigger expression of immune response genes
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NHL25 NHL3
Innate immunity – A common theme in mammals, Drosophila and plants (1) Pathogen-associated molecular patterns (PAMP) are recognized by pattern recognition receptors and trigger expression of immune response genes (Medzhitov, R & Janeway, CA (1997) Cell 91:295-8) LPS from gram-negative bacteria PGN from gram-positive bacteria Fungal glucans, chitin, proteins Eubacterial flagellin (often) abundant structures Surface-exposed structures Not present in hosts Evolutionarily conserved Crucial to the biology of the pathogen Institut of plant biochemistry
Innate immunity – A common theme in mammals, Drosophila and plants (2) Institute of Plant Biochemistry
Acknowledgement Justin Lee Annette Romanski Guido Fellbrich Magdalena Krzymowska Anne Varet Sabine Rosahl Carola Geiler Thorsten Nürnberger Dierk Scheel Collaborations: Sakari Kauppinen (Novo Nordisk A/S, Denmark) Grethe Rasmussen Francine Govers (University of Wageningen, The Netherlands) Jürg Felix (FMI Basel, Switzerland) Jeff Dangl (University of North Carolina, USA) KWS Einbeck, Germany Institute of Plant Biochemistry