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Scientific literacy- Module II, April 10, 2008. Jim Kennedy - Example of critical review of a paper Cobo et al, 2007 Sensitivity and specificity of culture and PCR of smegma samples of bulls experimentally infected with Tritrichomonas foetus , Theriogenolog y , 68:853-860.
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Scientific literacy- Module II, April 10, 2008 • Jim Kennedy - Example of critical review of a paper • Cobo et al, 2007 Sensitivity and specificity of culture and PCR of smegma • samples of bulls experimentally infected withTritrichomonasfoetus, • Theriogenology, 68:853-860. • 2. Dave Smith – Perspectives on scientific method • Jim Keen • - Results of your scientific literacy expectations • - Critical review of scientific literature guidelines • - Research Projects • * Crafting a literature review • * Searching the lit – PubMed, Agricola, Google, Google Scholar • * Review of project suggestions from Module I • * New project suggestions since Module I • * Choose your project and sign up
Your expectations for scientific literacy section 1. How to evaluate veterinary, scientific or product literature - Study design correct? Stats correct? Conclusions valid? - How do I critically evaluate product trials? Detect false results? - How do I rapidly assess a paper? - How do I assess clinical (vs statistical) significance from an article 2. Numeracy (=numerical literacy) - How do I convert numbers into data, and data into useful information - How do I use/analyze/interpret data that I gather in my practice or job? - What are some easy data gathering and analysis tools? - Can you provide me some straight forward biostatistics training 3. Practical epi - How can I catalog articles so I can find and use the information later - How do I run a quality trial, gather the data, interpret it, report it - How do I investigate herd outbreaks (morbidity, mortality) - How do I evaluate and interpret production data and herd records - How do I use herd records to make management decisions
How should we read a scientific paper? Title Author(s) Abstract/Conclusions RELEVANCE Materials and methods Objectives Data/ supporting evidence Outcomes Conclusions QUALITY
Determining relevance of an article (from DL Sackett) Look at the TITLE – Interesting or Useful? NO YES Review the AUTHORS – Good track record? Not relevant, so go to the next paper NO YES Read the SUMMARY – Potentially useful? NO YES Consider the SITE – Potentially applicable? NO YES Has RELEVANCE, so Critically Review
Scientific literacy – Oral presentations • Clinical epidemiology scientific paper review • Pairs of participants will identify, read, evaluate & lead discussion • of a scientific paper of their choosing • - Two papers will be discussed during each of the remaining five modules • All participants will read and discuss the papers • Guidelines for evaluation to be provided • Mentors will do first paper on during Module 2 • OR • Vet epi or public health in the news • Pairs of participants will trace the original source of an article in the • popular press • The popular vs original messages will be compared
Conducting a literature search - PubMed (National Library of Medicine) - Agricola (National Agriculture Library) - Google - Google Scholar
Scientific literacy - research projects • 1 Participatory clinical epidemiology – gain experience • - Journey not destination is important • 2 Evidence Based Vet Med • 3 Try to answer questions of personal interest or relevance • Small group of up to four persons • Often clinical or field trial • KISS – Keep it simple • 7 “Need to know” vs “nice to know”