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CELL STRUCTURE CH 6. Cells are the smallest collection of matter that is alive All living things are made of cells All cells descend from pre-existing cells All cells share several basic features. I. Why are cells so small? A. The surface – to – volume theory.
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CELL STRUCTURECH 6 Cells are the smallest collection of matter that is alive All living things are made of cells All cells descend from pre-existing cells All cells share several basic features
I. Why are cells so small?A. The surface – to – volume theory
Metabolic requirements limit cell size • Surface area to volume ratio of a cell is critical to its metabolic efficiency • Surface area increases by n2 while volume increases by n3 • Smaller cells have a larger surface area to volume ratio
B. How cells can increase in size without decreasing the SA/V ratio:
increase their surface area or decrease their volume • Organelles • Plant cells : large central vacuole • Nerve cells: long skinny extensions • Intestinal cells: highly folded cell membrane
II. Prokaryotic cells vs Eukaryotic cellsA. Prokaryotic cells • No nucleus or organelles • Circular DNA in a nucleoid region • Cytoplasm and ribosomes surrounded by cell membrane
B. Eukaryotic cells • Have linear chromosomes in nucleus • Organelles • Bigger than prokaryotic cells
C. All cells have: • Cell membrane to let things in and out • Ribosomes for protein synthesis • Cytoplasm where many enzymatic reactions occur • Chromosomes that contain genes
D. Cell wall: protection and support • in prokaryotic and some eukaryotic cells • cellulose in plants • chitin in fungi • peptidoglycan in bacteria (not archaea)
III. A Tour of Eukaryotic Cells • Eukaryotic cells have internal membranes forming organelles • This localizes cellular activities to different parts of cell • All eukaryotic cells have nearly the same organelles
A. The endomembrane system is composed of the nucleus, ER, Golgi, lysosomes, vacuoles, and cell membrane • 1. Evolution • most widely accepted model is thru invagination of the cell membrane
2. nucleus What are some structural features of nucleus?
contains most of the cell’s DNA • surrounded by nuclear envelope that is double membrane with pores • contains chromosomes and nucleolus (synthesize ribosomal RNA) • pores regulate what enters and leaves • What enters and leaves?
RNA that leaves nucleus is used by ribosome to make protein • Free ribosomes are in cytoplasm and make proteins that stay in cytoplasm • Bound ribosomes are on RER and make membrane bound proteins or proteins that leave the cell
3. endoplasmic reticulum (ER): the cell’s factory • highly folded membranecontinuous with nuclear membrane
types • rough ER (RER) • membrane is studded with ribosomes • it helps synthesize and modify proteins that will be transported • smooth ER (SER) • no ribosomes on it • it synthesizes carbs and lipids • it detoxifies drugs
Questions: • a. what type of cell would have a lot of RER? Why? • b. what type of cell would have a lot of SER? Why?
4. Golgi apparatus: shipping and receiving • Flatted stack of membranes found near the RER • It receives proteins from the RER and packages them for transport out of the cell
membrane bound organelles with digestive enzymes in acidic environment • digest macromolecules (phagocytosis) • digest and recycle old organelles (autophagy) • digest bacteria and viruses • digest cells destined to be destroyed (apoptosis)
6. Vacuoles: storage depots • Derived from ER and Golgi • Central vacuole in plants stores water and gives plant cell its rigid shape
B. Mitochondria and Chloroplasts: convert energy from one form to another 1. mitochondria • double membraned organelle where the inner membrane is folded into cristae • site of ATP synthesis via aerobic respiration • purpose of cristae?
2. chloroplast • double membraned organelle which contains stacks of membrane sacs (thylakoids) called grana • contain chlorophyll • use the energy from the sun to make a precursor to glucose by photosynthesis • purpose of thylakoids?
3. Evolutionary Origins of Mitochondria and Chloroplasts: Endosymbionttheory • Have similarities with bacteria • Have ribosomes and DNA similar in size and structure to bacteria • Same size • Divide independently from rest of cell http://www.sumanasinc.com/webcontent/animations/content/organelles.html