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Explore the history, theories, and mechanisms behind color vision, including the perception of primary colors, color mixing, and the role of cones in the photopic vision. Learn about color blindness and its different forms.
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The Special Senses -1433Vision – 3Color Vision Professor A.M.A Abdel Gader MD, PhD, FRCP (Lond., Edin), FRSH (London) Professor of Physiology, College of Medicine & King Khalid University Hospital Riyadh, Saudi Arabia
Color (Photopic)Vision ‘Young - Helmholtz theory’ ‘The Trichromatic theory’
History of color vision Newton (1704) used a prism to show that sunlight was composed of light with all colors in the rainbow. He defined it as the spectrum.
History ofcolorvision Primary colors: 723-647 575-492 492-450 Thomas Young 1807: primary colors: when mixed >>> white or any other color
Photopicvision (CONES) Helmholtz ..1860: The three primary colors are perceived by three photoreceptor pigments (with broad absorption curves) White light is produced by mixing the three primary colors
Cone wavelength ranges S M L Relative absorption 700 400 500 600 Wavelength (nm)
Photopicvision (CONES) Cone pigments: three kinds 565 535 440
PhotopicvisionYoung Helmholtz theory Color vision is subserved by three types of cones, each containing a photoreceptor pigment most sensitive to one primary color • Cones (contain red-sensitive pigment) • Cones (contain green-sensitive pigment) • Cones (contain blue-sensitive pigment) in the fovea centralis
Cone wavelength ranges S M L Relative absorption 700 400 500 600 Wavelength (nm)
Photopicvision Sensation of any color determined by: a-wavelength of light b-amount of light absorbed by each type of cones c-frequency of impulses from each cone system to ganglion cells which is determined by wave length of light.
Photopicvision perception of white is due to: equal stimulation of blue & red & green cones. (white is a combination of all wave lengths)
Color Blindness Weakness or total blindness in detecting a primary color: Definitions: • Trichromats: see the 3 1ry colors • Dichromats: blind to one 1ry color • Monochromats: have color pigment
Color Blindness –cont. • Prot …… Red • Deuter …. Green • Trit …… Blue • Anamoly …weakness • Protanamoly • Deuteranamoly Trichromats • Tritanamoly
Color Blindness –cont. • Anamoly …weakness • Anopia …. Total loss • Protanopia • Deuteranopia Dichromats • Tritanopia
Color Blindness –cont. • Prevalence: males ………….8% females …. 0.4% Inheritance: sex-linked due abnormal gene in the X chromosome
Light Change in photopigment Metarhodopsin II Activation of transducin Activation of phophodiesterase Decrease IC cyclic GMP Closure of Na channels Hyperpolarization of receptor Action potential in optic nerve fibres
Bleaching and Regeneration of Visual Pigments Figure 17.15
Electrophysiology of Vision Electric recording in Retinal cells: Bipolar cells: Hyper- & Depolarization Horizental cells: Hyper- & Depolarization Amacrine cells: Depolarizing potential Ganglion cells:Depolarizing potential