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ADPRT Reaction

ADPRT Reaction. NAD +. eEF2 diphthamide residue. nicotinamide. ADP-ribosylated eEF2 diphthamide residue. ADPRT Reaction. O. O. CH. 3. O. CH. N. CH. 3. NH. 3. H. N. +. 2. 2. CH. ADP-ribosyl-eEF-2. CH. N. 3. +. 3. H. N. +. N. 2. CH. CH. 3. 2. CH. H. O. 2. O.

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ADPRT Reaction

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  1. ADPRT Reaction NAD+ eEF2 diphthamide residue nicotinamide ADP-ribosylated eEF2 diphthamide residue

  2. ADPRT Reaction

  3. O O CH 3 O CH N CH 3 NH 3 H N + 2 2 CH ADP-ribosyl-eEF-2 CH N 3 + 3 H N + N 2 CH CH 3 2 CH H O 2 O O O H N N - eEF2 O P O - O P O : N N OH O OH OH O OH NH NH CH PROTEIN 2 2 2 - O P O - O P O N CH PROTEIN N N 2 N O O N N N N CH CH 2 O 2 O NAD+ O NH 2 OH OH OH N OH nicotinamide ADP-Ribosylation of eEF-2 by ETA

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